{"id":"W4379653690","doi":"10.1016/j.jaip.2023.03.027","title":"Reply to “Clinically accessible biomarkers to assess the modifiable risk of asthma/wheezing attacks in toddlers”","year":2023,"lang":"en","type":"letter","venue":"The Journal of Allergy and Clinical Immunology In Practice","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; Sanofi Genzyme; Genentech; Canadian Lung Association; National Institute of Nursing Research; Teva Pharmaceutical Industries; National Institute for Health and Care Research; Insmed; National Institutes of Health; Covis Pharma; Regeneron Pharmaceuticals; Lung Health Foundation; Sanofi; GlaxoSmithKline; AstraZeneca","keywords":"Medicine; Asthma; Exacerbation; Wheeze; Allergy; Pediatrics; Asthma exacerbations; Eosinophil; Bronchial hyperresponsiveness; Inhaled corticosteroids; Internal medicine; Immunology; Respiratory disease; Lung","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004559032,0.001064263,0.001792602,0.0008964233,0.003324592,0.002799029,0.001827426,0.04739818,0.003721058],"category_scores_gemma":[0.0284082,0.001053639,0.001350307,0.0007329726,0.002232932,0.002520885,0.001584759,0.04177279,0.004840905],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003138117,"about_ca_system_score_gemma":0.00439552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01069846,"about_ca_topic_score_gemma":0.01455635,"domain_scores_codex":[0.9968526,0.0009491675,0.0005981217,0.0004883832,0.0006630701,0.0004487566],"domain_scores_gemma":[0.9889076,0.00608889,0.0008368552,0.0003494405,0.002211087,0.001606039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001390752,0.00004365388,0.002448388,0.00006353874,0.00004262398,0.001468023,0.000156083,0.00005503815,0.0001928408,0.0009652543,0.988916,0.005509377],"study_design_scores_gemma":[0.0004367286,0.0002473489,0.01018479,0.0008664107,0.0001668631,0.003545931,0.001292056,0.0008845277,0.0005297465,0.00709408,0.9745385,0.0002129462],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0004591702,0.0006792295,0.00008434297,0.9763358,0.02142681,0.00001348533,0.0001277117,0.00002254608,0.0008508335],"genre_scores_gemma":[0.002025489,0.0004096239,0.0001562734,0.9764973,0.018826,0.00003913074,0.00003876159,0.00001308654,0.00199435],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.04739818,"threshold_uncertainty_score":0.02411073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06867666198635375,"score_gpt":0.4089882817475797,"score_spread":0.3403116197612259,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}