{"id":"W4379662223","doi":"10.1200/jco.2023.41.17_suppl.lba100","title":"KEYNOTE-671: Randomized, double-blind, phase 3 study of pembrolizumab or placebo plus platinum-based chemotherapy followed by resection and pembrolizumab or placebo for early stage NSCLC.","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Medicine; Pembrolizumab; Placebo; Randomization; Tolerability; Lung cancer; Population; Internal medicine; Stage (stratigraphy); Oncology; Surgery; Clinical trial; Cancer; Adverse effect; Pathology; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002294703,0.002385585,0.003163204,0.0007358964,0.0006969768,0.001448167,0.001652397,0.00292994,0.01271149],"category_scores_gemma":[0.00170336,0.001340664,0.001535812,0.000568539,0.001485729,0.001461884,0.0005391478,0.004613196,0.002253308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001075441,"about_ca_system_score_gemma":0.002369216,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001184604,"about_ca_topic_score_gemma":0.003741592,"domain_scores_codex":[0.9993578,0.0003229484,0.0000339226,0.0001181848,0.00005009094,0.0001171541],"domain_scores_gemma":[0.9991321,0.0002020906,0.0002120419,0.0000561318,0.00005578716,0.0003419771],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9742388,0.01236836,0.0001810937,0.0006793311,0.0003949747,0.00002731057,0.00003368664,0.000200111,0.003134518,0.0001241242,0.001088114,0.007529553],"study_design_scores_gemma":[0.958772,0.03985598,0.0003611556,0.00002125059,0.0001339493,0.00001547587,0.000008315979,0.0001640113,0.0002393427,0.00007121889,0.0003492471,0.000008087936],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9466474,0.006550749,0.002275629,0.001406619,0.001570355,0.02974025,0.00495075,0.000711288,0.006146897],"genre_scores_gemma":[0.9470672,0.004365161,0.004090056,0.003071921,0.0006851337,0.02881679,0.002482845,0.00009519051,0.009325651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01271149,"threshold_uncertainty_score":0.04252416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1590405190309529,"score_gpt":0.4880907807404934,"score_spread":0.3290502617095405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}