{"id":"W4379662306","doi":"10.1016/j.maturitas.2023.04.230","title":"MicroRNA-181a-5p negatively regulates glycolysis by silencing PGRMC1 and HIF1α in PGRMC1-overexpressing breast cancer cells","year":2023,"lang":"en","type":"article","venue":"Maturitas","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"","keywords":"Medicine; Gene silencing; Breast cancer; microRNA; Cancer; Cancer research; Cancer cell; Internal medicine; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001551169,0.0002365589,0.000273405,0.0001008414,0.000108849,0.00008033897,0.0001633721,0.0001961907,0.00006840142],"category_scores_gemma":[0.00002081129,0.0002366425,0.00008250287,0.0002812017,0.0001006649,0.00001559962,0.0001766599,0.0001480474,0.00001647027],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003470058,"about_ca_system_score_gemma":0.00006978624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006497902,"about_ca_topic_score_gemma":0.0002024674,"domain_scores_codex":[0.9985999,0.00005844995,0.0002422266,0.0005182291,0.0001457987,0.0004354136],"domain_scores_gemma":[0.9994462,0.00002254209,0.0001009534,0.0002699749,0.00005125664,0.0001090971],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007602083,0.00002315745,0.0003803017,0.00005082528,0.00004494658,0.000003584641,0.0002651541,0.00005144305,0.9482426,0.000006552139,0.04383682,0.007018605],"study_design_scores_gemma":[0.0009607099,0.00002550311,0.01816985,0.000122643,0.00004727165,0.00002148765,0.00033397,0.00008533985,0.8918196,0.0001086752,0.08790971,0.0003952585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855554,0.01256411,0.00001246534,0.0004032457,0.0005559366,0.0001789368,0.0003866264,0.00003542353,0.0003079075],"genre_scores_gemma":[0.9908751,0.00483302,0.0003163288,0.000338944,0.0008157283,0.00005241487,0.0001469053,0.00005418103,0.002567373],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.056423,"threshold_uncertainty_score":0.9650002,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005565491778742741,"score_gpt":0.229070089482068,"score_spread":0.2235045977033252,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}