{"id":"W4379662502","doi":"10.1016/j.maturitas.2023.04.029","title":"Treatment of moderate-to-severe vasomotor symptoms associated with menopause with fezolinetant: pooled responder analysis from SKYLIGHT 1 and 2","year":2023,"lang":"en","type":"article","venue":"Maturitas","topic":"Menopause: Health Impacts and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Medicine; Vasomotor; Menopause; Skylight; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.009138021,0.002059244,0.008092532,0.001203245,0.0003799389,0.001412488,0.0008282496,0.002019968,0.004966631],"category_scores_gemma":[0.008270061,0.001037405,0.02277468,0.001129832,0.0008618909,0.001449799,0.001227378,0.002526733,0.0004650654],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006935638,"about_ca_system_score_gemma":0.0006843047,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001670557,"about_ca_topic_score_gemma":0.004488387,"domain_scores_codex":[0.9923482,0.005053078,0.0008059638,0.0007946627,0.0004717752,0.0005263943],"domain_scores_gemma":[0.9945675,0.002645109,0.001449474,0.0007643753,0.0002936809,0.0002798742],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7786554,0.0006352254,0.009471333,0.008337973,0.1699292,0.0001123986,0.000113718,0.0007707968,0.002771441,0.0001127982,0.001640375,0.02744934],"study_design_scores_gemma":[0.4400429,0.05863347,0.1346708,0.00155084,0.3547459,0.0003098062,0.0003171284,0.001303997,0.001469739,0.0009153449,0.005778067,0.0002621172],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8152749,0.1577873,0.006288661,0.001005001,0.001445531,0.002415457,0.01100777,0.0003431946,0.004432319],"genre_scores_gemma":[0.9750614,0.0135101,0.002004738,0.001325012,0.000806571,0.001048355,0.004110475,0.00008732201,0.002046146],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009138021,"threshold_uncertainty_score":0.04832703,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01971031597116004,"score_gpt":0.2849964807020339,"score_spread":0.2652861647308739,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}