{"id":"W4379742689","doi":"10.1089/ipm.10.03.04","title":"One and Done? How CRISPR Is Changing the Clinical Outlook for Multiple Diseases","year":2023,"lang":"en","type":"article","venue":"Inside Precision Medicine","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"CARE Canada","funders":"","keywords":"CRISPR; Download; Medicine; Clinical microbiology; Family medicine; Internal medicine; Library science; Gerontology; Computer science; World Wide Web; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01752868,0.0009414913,0.001910086,0.001365204,0.001942686,0.008771498,0.001648004,0.006084696,0.006833088],"category_scores_gemma":[0.01451209,0.0005999314,0.001014607,0.0006912641,0.01037935,0.01298058,0.003646893,0.01738662,0.00245072],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002360878,"about_ca_system_score_gemma":0.004518904,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001568455,"about_ca_topic_score_gemma":0.003297574,"domain_scores_codex":[0.9937058,0.002493582,0.0003654486,0.0008771768,0.001855671,0.0007023925],"domain_scores_gemma":[0.9871079,0.006517488,0.0006736503,0.00139543,0.002190379,0.002115123],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008520227,0.000242379,0.002586104,0.002178677,0.000428672,0.00200911,0.001587766,0.001533606,0.01597287,0.2927996,0.2078868,0.4719224],"study_design_scores_gemma":[0.0001452894,0.0003467852,0.001125087,0.001531702,0.0002260369,0.003187521,0.001733004,0.000958112,0.005124686,0.2877294,0.6976756,0.0002167859],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.00464088,0.2228341,0.03419625,0.6939983,0.02738028,0.00003448434,0.0002277573,0.0007229841,0.0159649],"genre_scores_gemma":[0.166592,0.3305658,0.05626876,0.3787669,0.04299137,0.0001773531,0.0003194748,0.0009235864,0.02339487],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01752868,"threshold_uncertainty_score":0.09270167,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05277204017940281,"score_gpt":0.3914139401871078,"score_spread":0.3386419000077051,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}