{"id":"W4379780573","doi":"10.1021/acscatal.3c01713","title":"Chemoenzymatic Dynamic Kinetic Resolution of Secondary Alcohols and Amines Employing Copper-Based Photocatalysis","year":2023,"lang":"en","type":"article","venue":"ACS Catalysis","topic":"Radical Photochemical Reactions","field":"Chemistry","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre in Green Chemistry and Catalysis","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada","keywords":"Kinetic resolution; Candida antarctica; Racemization; Photocatalysis; Chemistry; Catalysis; Copper; Yield (engineering); Lipase; Radical; Organic chemistry; Combinatorial chemistry; Enantioselective synthesis; Enzyme; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002965539,0.0004959908,0.0003253791,0.0002240142,0.0001847081,0.0002914192,0.0004225993,0.0003507591,0.0007294804],"category_scores_gemma":[0.0002500461,0.0002548992,0.0002127993,0.0002717089,0.0003017793,0.0003289996,0.0003926312,0.0005740356,0.0003515589],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005461887,"about_ca_system_score_gemma":0.0003244529,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001554462,"about_ca_topic_score_gemma":0.002496658,"domain_scores_codex":[0.9997908,0.00002495582,0.00001484133,0.00005826707,0.00005741632,0.00005356579],"domain_scores_gemma":[0.999925,0.00001427789,0.00001488159,0.00001225053,0.00001786097,0.00001567745],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000044673,0.00001570251,0.00006269755,0.0000472424,0.000006388748,0.00004688593,0.00002038605,0.00008781946,0.9957193,0.0001214513,0.00007902112,0.003748511],"study_design_scores_gemma":[0.000003774473,0.00004066223,0.0001672344,9.491562e-7,0.000003661231,0.00005204634,0.000004168556,0.0002470775,0.9987292,0.00001168404,0.0007364801,0.000002963485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9613042,0.003168294,0.02599285,0.0002405908,0.0000701328,0.00013186,0.0004250336,0.0004536717,0.00821332],"genre_scores_gemma":[0.9835944,0.001318489,0.0112996,0.00004046753,0.00001445694,0.00003872207,0.0002354577,0.00002971683,0.003428742],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001554462,"threshold_uncertainty_score":0.003962874,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01403159573647478,"score_gpt":0.2631172954432061,"score_spread":0.2490856997067313,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}