{"id":"W4379793177","doi":"10.1136/annrheumdis-2023-eular.632","title":"AB1096 IMPROVEMENT IN KEY PSORIATIC ARTHRITIS CORE DOMAINS WITH GUSELKUMAB TREATMENT IN AN ENRICHED POPULATION OF ACR20 NON-RESPONDERS AT WEEK 24: POST HOC ANALYSIS OF TWO PHASE 3 STUDIES","year":2023,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Barrie Urology Group","funders":"Celgene; Gilead Sciences; Amgen; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Dactylitis; Psoriatic arthritis; Internal medicine; Post-hoc analysis; Population; Enthesitis; Rheumatology; Placebo; Gastroenterology; Rheumatoid arthritis; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003889594,0.001241635,0.004223342,0.000381065,0.0006128331,0.001021801,0.0005404954,0.0009917004,0.003363812],"category_scores_gemma":[0.002169627,0.0004610636,0.002831421,0.0004328421,0.0007667848,0.001038581,0.0005545801,0.001828496,0.0005018167],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004420317,"about_ca_system_score_gemma":0.0008597689,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006637403,"about_ca_topic_score_gemma":0.001451418,"domain_scores_codex":[0.9977677,0.001303542,0.0001257244,0.0003215664,0.0001378836,0.0003436736],"domain_scores_gemma":[0.9982535,0.0008057267,0.0002342088,0.0002598377,0.0001563521,0.0002902982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.9632637,0.005539732,0.004417024,0.0001999049,0.002373558,0.00005233223,0.00008020056,0.0003823461,0.01024904,0.00002363647,0.0002204638,0.01319811],"study_design_scores_gemma":[0.2515794,0.55875,0.1711915,0.0000542507,0.008558675,0.0001806373,0.0002542827,0.001868271,0.005921202,0.000228382,0.001310585,0.0001028432],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980757,0.0005528319,0.0002583454,0.00003866648,0.0000426071,0.0003779147,0.0002747692,0.0000234652,0.0003556006],"genre_scores_gemma":[0.9974651,0.0002279367,0.0004861369,0.0001060472,0.00005751453,0.0005280667,0.0004893122,0.00001607524,0.0006238156],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004223342,"threshold_uncertainty_score":0.02057034,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08217878608255655,"score_gpt":0.4041800652709043,"score_spread":0.3220012791883478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}