{"id":"W4379794110","doi":"10.1136/annrheumdis-2023-eular.515","title":"AB1084 GUSELKUMAB PROVIDES RAPID CLINICALLY MEANINGFUL IMPROVEMENTS IN CLINICAL AND PATIENT REPORTED OUTCOMES AND SUSTAINED DISEASE CONTROL OF PSORIATIC ARTHRITIS","year":2023,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto Western Hospital; McGill University","funders":"Bundesministerium für Bildung und Forschung; Janssen Scientific Affairs; Jazz Pharmaceuticals; Celgene; Novavax; Gilead Sciences; Sanofi; Amgen; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb; GlaxoSmithKline","keywords":"Medicine; Psoriatic arthritis; Quality of life (healthcare); Visual analogue scale; Dermatology Life Quality Index; Physical therapy; Psoriasis; Internal medicine; Ustekinumab; Placebo; Disease; Dermatology; Adalimumab; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000245274,0.0003966323,0.0007267641,0.0002107275,0.000140473,0.0003427547,0.0002794301,0.000405492,0.004508967],"category_scores_gemma":[0.0002351089,0.0001249404,0.0002875707,0.0001419647,0.0001631358,0.0003093722,0.0001708824,0.001355222,0.00126212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001783813,"about_ca_system_score_gemma":0.0002458941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004661781,"about_ca_topic_score_gemma":0.0007906461,"domain_scores_codex":[0.9998511,0.0000344196,0.000008856056,0.00001637091,0.00002785609,0.00006136496],"domain_scores_gemma":[0.9999098,0.00001300706,0.00001984605,0.00000775549,0.00000632946,0.00004338059],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.05599659,0.008960437,0.002373135,0.0007815789,0.0002910538,0.0006259021,0.00007737557,0.0006963314,0.3749677,0.0003738847,0.00725459,0.5476014],"study_design_scores_gemma":[0.08021983,0.2875161,0.2238195,0.000408457,0.00155936,0.009031778,0.0003593837,0.010005,0.3239538,0.001489977,0.06143818,0.0001985131],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9808527,0.0100485,0.001159251,0.0006722647,0.0003060428,0.0001105557,0.0004213514,0.0006157944,0.005813604],"genre_scores_gemma":[0.9933392,0.001898586,0.0006681456,0.0002526462,0.0001104111,0.00004494614,0.0004648173,0.00003194357,0.003189319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004508967,"threshold_uncertainty_score":0.01508403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03441002239376385,"score_gpt":0.3097852246297757,"score_spread":0.2753752022360119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}