{"id":"W4379794924","doi":"10.1136/annrheumdis-2023-eular.2516","title":"AB1088 EARLY CLINICAL IMPROVEMENT AS PREDICTOR OF LONG-TERM HEALTH-RELATED QUALITY OF LIFE IN PSORIATIC ARTHRITIS PATIENTS TREATED WITH GUSELKUMAB: POST-HOC ANALYSIS THROUGH 2 YEARS OF A PHASE-3 STUDY","year":2023,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; University of Saskatchewan","funders":"","keywords":"Dactylitis; Medicine; Psoriatic arthritis; Dermatology Life Quality Index; Enthesitis; Quality of life (healthcare); Internal medicine; Population; Physical therapy; Clinical endpoint; Visual analogue scale; Clinical trial; Arthritis; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004087425,0.001248035,0.003738683,0.0003841798,0.0005908594,0.001300421,0.0009424385,0.001095914,0.002631317],"category_scores_gemma":[0.002301715,0.0005487681,0.003068156,0.0005888186,0.0008176799,0.001326749,0.0007063568,0.002277325,0.0003929566],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005363313,"about_ca_system_score_gemma":0.001013325,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00191326,"about_ca_topic_score_gemma":0.00213094,"domain_scores_codex":[0.9974948,0.00142805,0.0001081899,0.0003966768,0.0001768718,0.0003954025],"domain_scores_gemma":[0.9976773,0.0009576686,0.0003904469,0.0002930631,0.0001963828,0.0004851976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9228474,0.004927001,0.05374904,0.0001420625,0.00351599,0.00009345415,0.0000979292,0.0006367135,0.004169631,0.00003535761,0.0002804981,0.00950489],"study_design_scores_gemma":[0.08697397,0.267395,0.6275648,0.00004899267,0.008614487,0.0001545728,0.0003116853,0.004462957,0.003082935,0.0001824421,0.001099602,0.0001085804],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987601,0.0004800374,0.0001285063,0.00003947202,0.00004651101,0.00008780181,0.000198576,0.00001156576,0.0002474087],"genre_scores_gemma":[0.9982796,0.0001782329,0.0001740218,0.00005902725,0.00006222267,0.000129787,0.0004323015,0.000007933987,0.0006769325],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004087425,"threshold_uncertainty_score":0.02161658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05840888493100015,"score_gpt":0.3587095173051938,"score_spread":0.3003006323741936,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}