{"id":"W4379796477","doi":"10.1097/01.hjh.0000941872.89649.71","title":"SALT-INDUCED VASCULAR DYSFUNCTION INVOLVES REDOX ACTIVATION OF PARP/TRPM2 SIGNALLING AND INFLAMMASOME ASSEMBLY","year":2023,"lang":"en","type":"article","venue":"Journal of Hypertension","topic":"Cardiovascular Disease and Adiposity","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Inflammasome; Medicine; Tiron; Mesenteric arteries; Apocynin; Reactive oxygen species; Vascular smooth muscle; Internal medicine; Pharmacology; Endocrinology; Oxidative stress; Cell biology; NADPH oxidase; Chemistry; Biochemistry; Inflammation; Biology; Artery; Superoxide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002734308,0.0004251538,0.0004446423,0.0002321712,0.0002123528,0.0004346224,0.0001996318,0.0005324924,0.002669215],"category_scores_gemma":[0.0001890915,0.0002033195,0.0006810942,0.0001633301,0.0003426168,0.0005059386,0.0003834791,0.0008110254,0.0003888124],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001878288,"about_ca_system_score_gemma":0.0001477142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001330381,"about_ca_topic_score_gemma":0.0001948105,"domain_scores_codex":[0.9996747,0.00005735044,0.00004247616,0.00007762912,0.00007877771,0.00006913721],"domain_scores_gemma":[0.9998191,0.00001520072,0.00007765218,0.00002053788,0.00002340941,0.00004407495],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000803771,0.00006972626,0.001175437,0.0001425453,0.00002730027,0.0002114211,0.00003573564,0.00003214541,0.9954412,0.00008773483,0.0001098874,0.001863131],"study_design_scores_gemma":[0.0001423154,0.002350405,0.07491381,0.00006995511,0.0001433617,0.001952111,0.000231154,0.001166067,0.9141253,0.0005116047,0.004369546,0.00002429791],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845029,0.006855844,0.005655425,0.0005542689,0.000134008,0.00005267191,0.0006444324,0.0001802585,0.001420202],"genre_scores_gemma":[0.9927807,0.002593532,0.002250864,0.0001884239,0.0000670868,0.00005413005,0.0004570132,0.00001583054,0.001592417],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002669215,"threshold_uncertainty_score":0.008929431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03478766981211883,"score_gpt":0.2430247260403008,"score_spread":0.208237056228182,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}