{"id":"W4379796608","doi":"10.1136/annrheumdis-2023-eular.1562","title":"POS1103 BIMEKIZUMAB MAINTAINED IMPROVEMENTS IN EFFICACY ENDPOINTS AND HAD A CONSISTENT SAFETY PROFILE THROUGH 52 WEEKS IN PATIENTS WITH NON-RADIOGRAPHIC AND RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS: RESULTS FROM TWO PARALLEL PHASE 3 STUDIES","year":2023,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"UCB Pharma","keywords":"Medicine; Axial spondyloarthritis; Ankylosing spondylitis; Internal medicine; Placebo; Radiography; Gastroenterology; Surgery; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003616883,0.001279256,0.002410546,0.0003194499,0.0004933763,0.001235878,0.000819194,0.001409954,0.003499993],"category_scores_gemma":[0.001912661,0.0006031621,0.002524216,0.000454834,0.0009083222,0.001513587,0.0003788755,0.003887766,0.00111597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008148755,"about_ca_system_score_gemma":0.00171836,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007593742,"about_ca_topic_score_gemma":0.002119671,"domain_scores_codex":[0.9989839,0.0004141265,0.0000958665,0.0001695922,0.0001236978,0.0002127906],"domain_scores_gemma":[0.9989598,0.0002422903,0.0002727501,0.0001465658,0.0001216675,0.0002568901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6913705,0.02736462,0.006896813,0.001565669,0.003989919,0.0002280045,0.0004074239,0.002650315,0.06654522,0.0003139699,0.005169865,0.1934976],"study_design_scores_gemma":[0.4875512,0.4530303,0.0389332,0.00009939517,0.001952653,0.0004362465,0.0001151942,0.001430268,0.01068061,0.0003598497,0.005305605,0.0001055652],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9887286,0.003133771,0.001320163,0.0005572341,0.000215968,0.00151551,0.001973598,0.00026317,0.002291974],"genre_scores_gemma":[0.9893752,0.001361595,0.002287074,0.001056711,0.0001479428,0.001076386,0.002480952,0.00008557486,0.002128528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003616883,"threshold_uncertainty_score":0.01912814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02776561906049646,"score_gpt":0.3126378686702236,"score_spread":0.2848722496097272,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}