{"id":"W4379796889","doi":"10.1136/annrheumdis-2023-eular.452","title":"POS1379 A NOVEL MEASURE OF END-STAGE KNEE OSTEOARTHRITIS REDUCES THE DURATION AND SAMPLE SIZE REQUIRED FOR OBSERVATIONAL STUDIES AND TRIALS","year":2023,"lang":"en","type":"article","venue":"","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Novo Nordisk; Pharmacy Guild of Australia; Nestlé Health Science; Pfizer; Eli Lilly and Company","keywords":"Osteoarthritis; WOMAC; Medicine; Observational study; Physical therapy; Knee replacement; Randomized controlled trial; Cohort study; Knee pain; Arthropathy; Arthroplasty; Internal medicine; Surgery; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.07319444,0.001104614,0.003867298,0.00178066,0.0004694184,0.002047837,0.001658447,0.002744497,0.02240285],"category_scores_gemma":[0.1729775,0.0008503667,0.002939471,0.002584699,0.0009600437,0.003142013,0.002097419,0.001948959,0.002726158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006934544,"about_ca_system_score_gemma":0.002608337,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003075903,"about_ca_topic_score_gemma":0.0007986816,"domain_scores_codex":[0.893196,0.08547334,0.01019938,0.005223442,0.005292424,0.0006154212],"domain_scores_gemma":[0.7990372,0.1635962,0.01618018,0.01241144,0.006413099,0.002361895],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.1196288,0.003094185,0.06084688,0.02235456,0.0248141,0.0008863229,0.0004173956,0.004780754,0.008285939,0.01578968,0.05237229,0.6867291],"study_design_scores_gemma":[0.188429,0.06190469,0.2473312,0.007400328,0.03898734,0.002613929,0.0008429303,0.05710544,0.007950548,0.08019868,0.3064895,0.000746435],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"methods","genre_scores_codex":[0.1911174,0.04488353,0.5890992,0.01884204,0.01507095,0.05630757,0.03437347,0.003586995,0.04671886],"genre_scores_gemma":[0.649464,0.00394406,0.2696224,0.007632737,0.004907968,0.05096058,0.007330748,0.0004071191,0.005730408],"genre_candidate":"methods","genre_consensus":"methods","teacher_disagreement_score":0.07319444,"threshold_uncertainty_score":0.3870938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2190120763390711,"score_gpt":0.3708835920627763,"score_spread":0.1518715157237052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}