{"id":"W4379799023","doi":"10.1136/annrheumdis-2023-eular.1918","title":"AB1087 LONG-TERM EFFICACY OF GUSELKUMAB IN FATIGUE AND IDENTIFICATION OF EARLY TREATMENT TARGETS: POST HOC ANALYSIS THROUGH 2 YEARS OF A PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY CONDUCTED IN BIOLOGIC-NAÏVE PATIENTS WITH ACTIVE PSORIATIC ARTHRITIS","year":2023,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal General Hospital; Toronto Western Hospital","funders":"","keywords":"Medicine; Post-hoc analysis; Double blind; Placebo; Randomized controlled trial; Term (time); Physical therapy; Internal medicine; Alternative medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004602596,0.001435529,0.004928776,0.0005357307,0.0006461695,0.0009649539,0.000918804,0.001509333,0.003211478],"category_scores_gemma":[0.002397644,0.0007073979,0.003439202,0.0005305333,0.001330368,0.001452502,0.0005371435,0.002724488,0.0006011568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006361161,"about_ca_system_score_gemma":0.001117456,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001082525,"about_ca_topic_score_gemma":0.001895519,"domain_scores_codex":[0.9980381,0.001108512,0.0001354559,0.000270191,0.000133619,0.0003141195],"domain_scores_gemma":[0.9977277,0.000873721,0.0004056366,0.0003133475,0.0001888024,0.0004908785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9799217,0.005057033,0.00135315,0.0001789631,0.001357312,0.00002465415,0.00003439271,0.0003218249,0.004093272,0.000020622,0.000132884,0.007504168],"study_design_scores_gemma":[0.569667,0.3943833,0.02750177,0.00003424127,0.003974033,0.00005974061,0.00006714909,0.0009853034,0.002662614,0.00010415,0.0005132976,0.00004750752],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966074,0.001788863,0.0002426785,0.00008453902,0.00009236372,0.0004188101,0.0004044428,0.00003020029,0.0003307098],"genre_scores_gemma":[0.9964908,0.0007378646,0.0004172394,0.0001655611,0.0001550517,0.000663441,0.0006348972,0.00001666467,0.0007185579],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004928776,"threshold_uncertainty_score":0.02434117,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0496325501211056,"score_gpt":0.3535877099984017,"score_spread":0.3039551598772961,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}