{"id":"W4379806113","doi":"10.1016/j.bbrep.2023.101498","title":"Nodding syndrome is unlikely to be an autoimmune reaction to leiomodin-1 after infection by Onchocerca volvulus","year":2023,"lang":"en","type":"article","venue":"Biochemistry and Biophysics Reports","topic":"Parasitic Diseases Research and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"","keywords":"Onchocerca volvulus; Biology; Immunostaining; Immunology; Trichinella spiralis; Antibody; Immunohistochemistry; Neurodegeneration; Autoimmunity; Autoantibody; Pathology; Onchocerciasis; Cell biology; Antigen; Disease; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002445793,0.0003868856,0.000251216,0.0004092158,0.0003141135,0.0001824223,0.0002186664,0.0006818592,0.001762206],"category_scores_gemma":[0.001067855,0.0001676988,0.0002487755,0.0001271532,0.0006281721,0.0004168192,0.0002609217,0.0003080231,0.0002172356],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00019318,"about_ca_system_score_gemma":0.0001572768,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005333511,"about_ca_topic_score_gemma":0.0005089702,"domain_scores_codex":[0.9998655,0.00001965861,0.00001728247,0.00003893783,0.00001573934,0.00004288539],"domain_scores_gemma":[0.9996186,0.0001065402,0.000142916,0.00003658309,0.00002824217,0.00006704756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00152563,0.0002139821,0.4184354,0.000516007,0.0001334694,0.4216729,0.0007601539,0.0001303788,0.1392808,0.001017272,0.0006059019,0.01570809],"study_design_scores_gemma":[0.0000784457,0.001133107,0.4516467,0.0001005383,0.0001013836,0.5323451,0.0004574838,0.0004434281,0.01031241,0.0004377119,0.002922289,0.000021396],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969241,0.000738745,0.0002945577,0.0001005813,0.00002000563,0.00001696477,0.00002661973,0.00002243309,0.001855977],"genre_scores_gemma":[0.9992039,0.0002058673,0.0001460305,0.00006491942,0.00001633847,0.000006355139,0.00003961699,0.000002357309,0.0003147352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001762206,"threshold_uncertainty_score":0.005895197,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01893038750776925,"score_gpt":0.3219965865484874,"score_spread":0.3030661990407181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}