{"id":"W4379806113","doi":"10.1016/j.bbrep.2023.101498","title":"Nodding syndrome is unlikely to be an autoimmune reaction to leiomodin-1 after infection by Onchocerca volvulus","year":2023,"lang":"en","type":"article","venue":"Biochemistry and Biophysics Reports","topic":"Parasitic Diseases Research and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"","keywords":"Onchocerca volvulus; Biology; Immunostaining; Immunology; Trichinella spiralis; Antibody; Immunohistochemistry; Neurodegeneration; Autoimmunity; Autoantibody; Pathology; Onchocerciasis; Cell biology; Antigen; Disease; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001034258,0.0001851735,0.0002152798,0.00008354431,0.0001054961,0.00005564656,0.00002913109,0.00009185054,0.00003596294],"category_scores_gemma":[0.00005731033,0.0001704465,0.00007936258,0.0005001901,0.00003625695,0.0001036111,0.00006507082,0.0000964564,0.00005601173],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001630358,"about_ca_system_score_gemma":0.0001074818,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002591805,"about_ca_topic_score_gemma":0.000001391812,"domain_scores_codex":[0.9985809,0.0000106279,0.0002242575,0.0005095184,0.0003497034,0.0003249334],"domain_scores_gemma":[0.9988421,0.00001151172,0.00005692764,0.0004053013,0.0001020855,0.0005821001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002454608,0.0003917257,0.01014319,0.0001344057,0.000112667,0.002013227,0.0001146525,0.000001145546,0.9763995,0.000001290653,0.004123617,0.006319105],"study_design_scores_gemma":[0.0005156342,0.0008002512,0.2394857,0.000206579,0.0001572616,0.001078705,0.00007812443,0.00008398874,0.7491124,0.00007633832,0.00803989,0.0003651606],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975811,0.00007156972,0.00002161555,0.001103394,0.0001062664,0.0003281402,0.00007923519,0.0001405167,0.0005681702],"genre_scores_gemma":[0.9953943,0.00004640835,0.00004631673,0.0003643826,0.00009181554,0.0001346561,0.0004729343,0.00002078141,0.003428437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2293425,"threshold_uncertainty_score":0.6950606,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01893038750776925,"score_gpt":0.3219965865484874,"score_spread":0.3030661990407181,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}