{"id":"W4379967054","doi":"10.1242/dev.201484","title":"A chromatin remodelling SWI/SNF subunit, Snr1, regulates neural stem cell determination and differentiation","year":2023,"lang":"en","type":"article","venue":"Development","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Azrieli Foundation; National Institutes of Health; University of Alberta","keywords":"Neuroepithelial cell; Biology; Neural stem cell; Chromatin; Stem cell; Cell biology; Cellular differentiation; Neural development; Multipotent Stem Cell; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001370124,0.0001193278,0.00009086095,0.0000527645,0.0001200683,0.00003387615,0.00006688807,0.00008006379,0.000004915209],"category_scores_gemma":[0.000004997687,0.0001161298,0.00002490065,0.00008873692,0.00001517262,0.000004635812,0.00007338596,0.0000413852,0.00001108086],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002580997,"about_ca_system_score_gemma":0.00004557201,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004286376,"about_ca_topic_score_gemma":0.00001122918,"domain_scores_codex":[0.9992256,0.00002687749,0.0002007574,0.0002498133,0.0001259119,0.0001710752],"domain_scores_gemma":[0.9996985,0.000008894999,0.00007129084,0.0001296187,0.00004603789,0.00004566896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003004319,0.00003258318,0.001951768,0.000167838,0.00002641367,0.000003520468,0.00141581,0.002948817,0.8100052,0.000006487841,0.0005627352,0.1828487],"study_design_scores_gemma":[0.0005064105,0.00004911263,0.02040623,0.00005256711,0.00001277787,0.00000872378,0.0001865231,0.2286752,0.7476474,0.00004648578,0.00211806,0.0002905296],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961272,0.0002728357,0.003187753,0.00004695509,0.00009990121,0.0001136756,0.000002258239,0.00004687047,0.0001025837],"genre_scores_gemma":[0.9962595,0.0001466913,0.001881054,0.0000409863,0.00005737165,0.00002218405,0.0002165201,0.00001869008,0.001357026],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2257264,"threshold_uncertainty_score":0.4735636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01520140583873145,"score_gpt":0.2297914371868884,"score_spread":0.2145900313481569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}