{"id":"W4379981345","doi":"10.1002/hon.3166_ot29","title":"LOTIS‐5, AN ONGOING PHASE 3 RANDOMIZED STUDY OF LONCASTUXIMAB TESIRINE WITH RITUXIMAB (LONCA‐R) VERSUS IMMUNOCHEMOTHERAPY IN PATIENTS WITH <i>R</i>/<i>R</i> DLBCL","year":2023,"lang":"en","type":"article","venue":"Hematological Oncology","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"","keywords":"Medicine; Rituximab; Internal medicine; Oncology; Clinical endpoint; Diffuse large B-cell lymphoma; Phases of clinical research; Refractory (planetary science); Neutropenia; Randomized controlled trial; Lymphoma; Clinical trial; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003330081,0.002001596,0.002060914,0.0005287484,0.0004964165,0.001629634,0.001382964,0.002409425,0.008250787],"category_scores_gemma":[0.001708169,0.0007298893,0.003133733,0.0004270811,0.001124759,0.00165094,0.0005479029,0.004457249,0.001806619],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001604691,"about_ca_system_score_gemma":0.001799378,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001118897,"about_ca_topic_score_gemma":0.003278985,"domain_scores_codex":[0.9991654,0.0004555029,0.00004179225,0.0001164529,0.0000774223,0.0001433662],"domain_scores_gemma":[0.9985464,0.0002917088,0.0004098371,0.0000883031,0.00009338628,0.000570244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9373066,0.02187649,0.001730756,0.0008421193,0.001856834,0.00006760378,0.0001080911,0.0006881854,0.004945173,0.0002575331,0.002930288,0.02739039],"study_design_scores_gemma":[0.8842518,0.1103303,0.002349894,0.00005270891,0.0005292114,0.00006400578,0.000036301,0.0004084285,0.0004529519,0.0002580629,0.001245651,0.00002071225],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9710965,0.007113747,0.0009777158,0.002386252,0.0009261159,0.009123501,0.003354483,0.0002639353,0.004757721],"genre_scores_gemma":[0.9627489,0.003951659,0.003608711,0.00613815,0.0008371297,0.01294809,0.004728561,0.00007080392,0.004968066],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008250787,"threshold_uncertainty_score":0.0276016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03914161227868253,"score_gpt":0.3791918403689819,"score_spread":0.3400502280902994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}