{"id":"W4379981851","doi":"10.1002/hon.3163_146","title":"IMMUNE CONTEXTURE ANALYSIS IN POLARIX SUGGESTS RESPONSE TO POLA‐R‐CHP TREATMENT REDUCES TUMOR MICROENVIRONMENT DEPENDENCY","year":2023,"lang":"en","type":"article","venue":"Hematological Oncology","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Roche (Canada)","funders":"","keywords":"International Prognostic Index; Rituximab; Vincristine; Medicine; Diffuse large B-cell lymphoma; Cyclophosphamide; Internal medicine; Prednisone; CHOP; Tumor microenvironment; Immune system; Lymphoma; Oncology; Hazard ratio; CD20; Gastroenterology; Cancer research; Immunology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0009702436,0.0004589148,0.001527259,0.0008365074,0.0002017162,0.00001659696,0.0005579717,0.0007618741,0.002543947],"category_scores_gemma":[0.0004184723,0.0003603378,0.000398698,0.001482938,0.0003912082,0.00005742364,0.000374229,0.0005710649,0.005029882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001052773,"about_ca_system_score_gemma":0.0002162188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003885785,"about_ca_topic_score_gemma":0.0005478848,"domain_scores_codex":[0.9953642,0.001551117,0.0009475345,0.0009275823,0.00008594283,0.001123581],"domain_scores_gemma":[0.9975933,0.00134835,0.0002473061,0.0006783618,0.00004028605,0.00009243239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.006191079,0.001402929,0.03311495,0.00001547089,0.001338801,0.002156357,0.001641519,0.0001779679,0.945315,0.0004182668,0.002793473,0.005434166],"study_design_scores_gemma":[0.006355666,0.004816273,0.4036872,0.00005867146,0.0006751122,0.001039351,0.001989899,0.00001407245,0.2951913,0.0003133126,0.2848842,0.0009749426],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859132,0.006205544,0.00002437712,0.005265481,0.0008755797,0.0007699133,0.00007697834,0.0002016101,0.0006673745],"genre_scores_gemma":[0.9928121,0.0003745494,0.0002622341,0.0007774626,0.00002289251,0.0003493458,0.000204786,0.00003014082,0.005166518],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6501237,"threshold_uncertainty_score":0.9998848,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01990527309035667,"score_gpt":0.3052595588217014,"score_spread":0.2853542857313447,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}