{"id":"W4379981852","doi":"10.1002/hon.3166_ot28","title":"PHASE 3 TRIAL OF SUBCUTANEOUS EPCORITAMAB + R‐CHOP VERSUS R‐CHOP IN PATIENTS (PTS) WITH NEWLY DIAGNOSED DIFFUSE LARGE B‐CELL LYMPHOMA (DLBCL): EPCORE DLBCL‐2","year":2023,"lang":"en","type":"article","venue":"Hematological Oncology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC; University of British Columbia","funders":"National Institutes of Health; National Cancer Institute; Celgene; Bristol-Myers Squibb","keywords":"Medicine; Internal medicine; Rituximab; Diffuse large B-cell lymphoma; Vincristine; Cytokine release syndrome; Oncology; Prednisone; CHOP; International Prognostic Index; Cyclophosphamide; Phases of clinical research; CD20; Lymphoma; Discontinuation; Gastroenterology; Clinical trial; Chemotherapy; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001542606,0.001940556,0.0017751,0.0002856473,0.0003188195,0.001031447,0.0009639435,0.001190194,0.005542737],"category_scores_gemma":[0.001031003,0.0005843755,0.00132476,0.0003314195,0.0009241509,0.0008370545,0.0004009505,0.004449605,0.001489863],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008989691,"about_ca_system_score_gemma":0.00128654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001120435,"about_ca_topic_score_gemma":0.002846234,"domain_scores_codex":[0.9996784,0.0001695026,0.00001056271,0.00005462499,0.00002483282,0.00006211377],"domain_scores_gemma":[0.999428,0.0001153357,0.0001038677,0.00005487726,0.00003025516,0.0002676332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9219002,0.02358753,0.001537584,0.0004901231,0.000761205,0.0001239116,0.0001254895,0.001315842,0.009798429,0.000224059,0.003433753,0.03670191],"study_design_scores_gemma":[0.8509995,0.142425,0.003263655,0.00002606717,0.0002418754,0.0001238539,0.00002937141,0.0009786002,0.0006384714,0.0002148586,0.001042964,0.00001589423],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871922,0.002012041,0.0006604421,0.0009065474,0.0004089741,0.003391447,0.001707352,0.0002460768,0.00347505],"genre_scores_gemma":[0.9835801,0.001453862,0.001727876,0.001609623,0.0002999625,0.003863232,0.003270995,0.00004905989,0.004145272],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005542737,"threshold_uncertainty_score":0.01854229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04596949735079359,"score_gpt":0.360199123689225,"score_spread":0.3142296263384314,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}