{"id":"W4379983361","doi":"10.1158/1538-7445.am2023-3387","title":"Abstract 3387: ctDNA dynamics in early stage node negative lung cancers","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Medicine; Circulating tumor DNA; Stage (stratigraphy); Internal medicine; Lung cancer; Occult; Oncology; Prospective cohort study; Lung; Primary tumor; Gastroenterology; Cancer; Surgery; Metastasis; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003053061,0.0002315252,0.0003311413,0.0005270698,0.0002017369,0.0006385508,0.0001918962,0.0004120179,0.0044759],"category_scores_gemma":[0.001195832,0.0001137916,0.0001171614,0.0005123267,0.0001674807,0.0003319599,0.0002260911,0.0003245367,0.001075686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003411991,"about_ca_system_score_gemma":0.0002046628,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001275754,"about_ca_topic_score_gemma":0.001046847,"domain_scores_codex":[0.9998664,0.00002204283,0.00001285485,0.00003570529,0.00004114493,0.00002189613],"domain_scores_gemma":[0.9994418,0.000122239,0.0002004953,0.00002360378,0.000108952,0.0001029001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002248881,0.000130568,0.9418027,0.0001796302,0.00004057559,0.0007665769,0.0001632051,0.0002726626,0.02558817,0.00008086021,0.001301034,0.02742504],"study_design_scores_gemma":[0.00005307132,0.0007049197,0.9867807,0.00003001222,0.00003288803,0.002372055,0.00008801619,0.0005236347,0.006049043,0.0001044893,0.003251101,0.00001001074],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938246,0.001669754,0.000373755,0.0001358311,0.00002303232,0.00003234788,0.001716809,0.00003072966,0.002193163],"genre_scores_gemma":[0.9963952,0.0003452704,0.000326205,0.00006592486,0.00003304863,0.00003154265,0.001312573,0.000009349519,0.001480996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0044759,"threshold_uncertainty_score":0.01497334,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03800442296135572,"score_gpt":0.3823281585093177,"score_spread":0.344323735547962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}