{"id":"W4379983529","doi":"10.1158/1538-7445.am2023-339","title":"Abstract 339: Exploring the roles of GSDMD in mammary tumorigenesis","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Carcinogenesis; Cancer; Pyroptosis; Breast cancer; Medicine; Cancer research; Bioinformatics; Oncology; Internal medicine; Inflammation; Biology; Inflammasome","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002340151,0.000551287,0.0003455071,0.0006255705,0.0002484354,0.0006389664,0.0003575691,0.0005123593,0.007296618],"category_scores_gemma":[0.0001198304,0.0001527887,0.0004549838,0.0006944815,0.0002073008,0.0003709242,0.0003721022,0.0007508608,0.001836092],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000740736,"about_ca_system_score_gemma":0.0004749217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001054099,"about_ca_topic_score_gemma":0.001216306,"domain_scores_codex":[0.9999272,0.000009967988,0.000004413631,0.00001723956,0.00002522768,0.00001592477],"domain_scores_gemma":[0.9999487,0.00000690387,0.000009097695,0.00000340944,0.00001368289,0.00001811978],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001642752,0.0002583447,0.005543895,0.001619268,0.00007120195,0.001117403,0.00006960432,0.0003745296,0.8708536,0.001813515,0.02070191,0.09593402],"study_design_scores_gemma":[0.00035752,0.001479133,0.1006473,0.0003121588,0.0003107847,0.003792997,0.000364193,0.002574878,0.5625956,0.002646616,0.3248635,0.00005529702],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5868981,0.2929995,0.01788545,0.02207737,0.004118229,0.0004700921,0.01677671,0.001011669,0.05776279],"genre_scores_gemma":[0.6984739,0.2039705,0.01639245,0.003692338,0.001282414,0.0002039094,0.01939556,0.00009584343,0.05649309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007296618,"threshold_uncertainty_score":0.02440965,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08509545731183157,"score_gpt":0.3701428594342678,"score_spread":0.2850474021224363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}