{"id":"W4379984540","doi":"10.1158/1538-7445.am2023-333","title":"Abstract 333: Interleukin 23 receptor is a critical regulator of the mitotic spindle and necessary for AML viability","year":2023,"lang":"en","type":"article","venue":"Cancer Research","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Cell biology; Mitosis; Biology; Flow cytometry; Intracellular; Regulator; Centrosome; Molecular biology; Cell; Cell cycle; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007338125,0.0003736344,0.0002963371,0.0002717045,0.0002469716,0.0003585349,0.0001605282,0.0002906235,0.006899184],"category_scores_gemma":[0.0001402915,0.0001033593,0.0002786219,0.0001597125,0.0001267836,0.000114479,0.0001643711,0.0003731432,0.002857951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000403061,"about_ca_system_score_gemma":0.0002185653,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006668211,"about_ca_topic_score_gemma":0.0006188266,"domain_scores_codex":[0.9998965,0.00001109115,0.000007974853,0.00002115343,0.00004600235,0.00001724774],"domain_scores_gemma":[0.999934,0.000008959463,0.00002036501,0.000004143412,0.00001350693,0.00001905433],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001275456,0.00001516238,0.0005545413,0.00004590604,0.000007165601,0.0002556478,0.000005484927,0.00007042353,0.9955616,0.00007682398,0.0004008525,0.00287896],"study_design_scores_gemma":[0.00005834153,0.0002822209,0.02448873,0.00002444962,0.00005028246,0.002165656,0.000052001,0.002490746,0.9483359,0.0001569376,0.02188237,0.00001222573],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9704167,0.007511879,0.005537475,0.0009067171,0.0001865715,0.00007173584,0.003980873,0.0004514873,0.01093649],"genre_scores_gemma":[0.9746446,0.002396526,0.004594416,0.0002902376,0.00005899217,0.00004429186,0.005854387,0.00006154038,0.0120551],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006899184,"threshold_uncertainty_score":0.02308005,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1203317775107203,"score_gpt":0.4656050694423401,"score_spread":0.3452732919316198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}