{"id":"W4379985328","doi":"10.21203/rs.3.rs-3007766/v1","title":"Detection of APP gene recombinant in human blood plasma","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics","keywords":"Amyloid precursor protein; Gene; Messenger RNA; Molecular biology; genomic DNA; Biology; Recombinant DNA; DNA; Pathogenesis; Amyloid (mycology); Alzheimer's disease; Disease; Genetics; Medicine; Pathology; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000529345,0.0003234815,0.0002944121,0.0003900786,0.0002243746,0.0004356769,0.0001471597,0.0005288686,0.0009510189],"category_scores_gemma":[0.001344499,0.0001447022,0.000251517,0.0003360038,0.000209989,0.0001536255,0.000230217,0.0003873919,0.0008501306],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001711872,"about_ca_system_score_gemma":0.0001869253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004983902,"about_ca_topic_score_gemma":0.0004164191,"domain_scores_codex":[0.9994771,0.00008836645,0.00003566108,0.0001845145,0.000169746,0.00004466613],"domain_scores_gemma":[0.9994715,0.0002634007,0.00008324513,0.00004983581,0.00009884933,0.00003316907],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009671658,0.0000145813,0.001424728,0.00003304131,0.000005589426,0.00009934107,0.00004571535,0.00008744492,0.9958754,0.00004519775,0.00005752596,0.002214593],"study_design_scores_gemma":[0.00001606646,0.0003806712,0.01515754,0.00001058731,0.00002146693,0.0007371746,0.00009199644,0.002911293,0.9780336,0.0002045103,0.00242509,0.000009998123],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9683498,0.000812085,0.02642589,0.00009745708,0.00004927184,0.00007653557,0.002198749,0.0004828445,0.001507322],"genre_scores_gemma":[0.910539,0.0005688163,0.07923329,0.0002242919,0.00003474893,0.0001509586,0.005923721,0.0001365742,0.003188577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009510189,"threshold_uncertainty_score":0.003181458,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1117250004058463,"score_gpt":0.4239558548265233,"score_spread":0.3122308544206771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}