{"id":"W4380049821","doi":"10.3390/vetsci10060390","title":"A Study of 41 Canine Orthologues of Human Genes Involved in Monogenic Obesity Reveals Marker in the ADCY3 for Body Weight in Labrador Retrievers","year":2023,"lang":"en","type":"article","venue":"Veterinary Sciences","topic":"Human-Animal Interaction Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Narodowym Centrum Nauki; Narodowe Centrum Nauki","keywords":"Obesity; Labrador Retriever; Allele; Biology; Overweight; Gene; Genetics; Neutering; Population; Genetic predisposition; Physiology; Medicine; Internal medicine; Endocrinology; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003844634,0.0002590597,0.000345924,0.0006773556,0.0002671772,0.000290547,0.0001802331,0.000314572,0.001748087],"category_scores_gemma":[0.0007943779,0.0001169586,0.0006553049,0.0007115097,0.0002268913,0.00008540919,0.0001833166,0.0002053867,0.0002266279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001768717,"about_ca_system_score_gemma":0.0002173821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003290356,"about_ca_topic_score_gemma":0.004382634,"domain_scores_codex":[0.9996738,0.00006672377,0.00002932788,0.0001421465,0.0000510972,0.00003684344],"domain_scores_gemma":[0.9996418,0.0001699749,0.00008886503,0.00003974806,0.00001825047,0.00004137876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003489084,0.0002042334,0.7684699,0.0002272948,0.0009108193,0.004707693,0.001824468,0.001665725,0.1867719,0.0006609532,0.0004395732,0.03062829],"study_design_scores_gemma":[0.00004149533,0.0001881218,0.9900798,0.00002198747,0.0003223418,0.001933273,0.0001973294,0.001432569,0.003481001,0.00008483246,0.002206623,0.00001062265],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985978,0.0003113405,0.0005464792,0.00001900332,0.000002685881,0.000005261625,0.0003440235,0.000006184745,0.0001671451],"genre_scores_gemma":[0.9975116,0.0001291417,0.001101525,0.00003270731,0.000007436883,0.00001180777,0.0008411672,0.00001106708,0.0003535252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003290356,"threshold_uncertainty_score":0.006542385,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08307913629391668,"score_gpt":0.3890536264622705,"score_spread":0.3059744901683538,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}