{"id":"W4380050038","doi":"10.1177/20543581231165716","title":"Minimal Kidney Disease Phenotype in <i>Shroom3</i> Heterozygous Null Mice","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Kidney Health and Disease","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; Toronto General Hospital; University Health Network; McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Kidney Foundation of Canada; McMaster University","keywords":"Kidney; Kidney disease; Heterozygote advantage; Biology; Pathology; Epithelium; Internal medicine; Endocrinology; Immunofluorescence; Kidney development; Null allele; Phenotype; Medicine; Allele; Immunology; Genetics; Gene; Antibody","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004192524,0.000882286,0.0006559616,0.001676062,0.0005814645,0.0006438841,0.0007342572,0.001473052,0.008055713],"category_scores_gemma":[0.0002951462,0.0004779372,0.0008306709,0.0004091573,0.0008991756,0.0003770232,0.0006761486,0.001550795,0.002044779],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004730194,"about_ca_system_score_gemma":0.0004311092,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001023476,"about_ca_topic_score_gemma":0.001650809,"domain_scores_codex":[0.9993985,0.00005133009,0.00008915932,0.0002018913,0.0001624732,0.00009667591],"domain_scores_gemma":[0.9990445,0.0001194767,0.0003965733,0.00005418056,0.00005409718,0.0003311652],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003536438,0.0001167265,0.0007595748,0.00007963874,0.00003049339,0.001042333,0.00007450452,0.0001006772,0.9954152,0.0004247685,0.0002631375,0.001339263],"study_design_scores_gemma":[0.0004990571,0.001380058,0.0521158,0.000170561,0.0002577753,0.02041641,0.0003288029,0.003154124,0.9051745,0.0008659053,0.01553353,0.0001034914],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9772277,0.0008175409,0.009532742,0.0004057035,0.0001493916,0.0001493947,0.007071365,0.001031494,0.003614763],"genre_scores_gemma":[0.9566927,0.001088445,0.01377195,0.0004896362,0.00008863938,0.0004529213,0.006954446,0.001003652,0.01945761],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008055713,"threshold_uncertainty_score":0.02694905,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008093675214497737,"score_gpt":0.244065325073234,"score_spread":0.2359716498587363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}