{"id":"W4380052902","doi":"10.2147/ijn.s406314","title":"The αTSR Domain of Plasmodium Circumsporozoite Protein Bound Heparan Sulfates and Elicited High Titers of Sporozoite Binding Antibody After Displayed by Nanoparticles","year":2023,"lang":"en","type":"article","venue":"International Journal of Nanomedicine","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"College of Medicine, University of Cincinnati; Cincinnati Children's Hospital Medical Center; National Institutes of Health; University of Cincinnati; National Institute of Allergy and Infectious Diseases; Johns Hopkins University; National Center for Advancing Translational Sciences; Purdue University","keywords":"Circumsporozoite protein; Titer; Antibody; Virology; Antibody titer; Chemistry; Biology; Cell biology; Immunology; Epitope","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001082764,0.0005195789,0.0001564335,0.00013147,0.00007208043,0.0001239676,0.000144326,0.0002909012,0.0007329003],"category_scores_gemma":[0.00007279267,0.0001089425,0.0002263036,0.00007967529,0.0001210174,0.0001081887,0.0001668326,0.0003707604,0.0002831911],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002321499,"about_ca_system_score_gemma":0.0001135569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000535343,"about_ca_topic_score_gemma":0.0007137539,"domain_scores_codex":[0.9999051,0.00001085049,0.000006258889,0.00002523925,0.00002844163,0.00002403344],"domain_scores_gemma":[0.9999523,0.000006726405,0.00001262414,0.000005250433,0.00001134627,0.00001175219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000150967,0.000007811747,0.00004867219,0.00001359902,0.000002305003,0.00001285048,0.000004165232,0.00002929208,0.9995587,0.0000201113,0.00001482272,0.0002725285],"study_design_scores_gemma":[0.000006300518,0.0002098938,0.001193988,0.000003782725,0.000008837551,0.00009497929,0.000007442397,0.0008253081,0.9966559,0.00001203375,0.0009794848,0.000002073504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927032,0.0005380076,0.004838085,0.00005387123,0.00002149534,0.00003135739,0.0001367193,0.00005176103,0.001625555],"genre_scores_gemma":[0.9928456,0.0003750778,0.003500343,0.00007245201,0.000007534554,0.00001793732,0.0005301281,0.00001657465,0.002634203],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007329003,"threshold_uncertainty_score":0.002451777,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008850670762382128,"score_gpt":0.3082915370520796,"score_spread":0.2994408662896975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}