{"id":"W4380083674","doi":"10.1002/hon.3164_204","title":"Impact of the Dark Zone Signature on Central Nervous System Relapse in a Real‐World Diffuse Large B‐cell Lymphoma Population","year":2023,"lang":"en","type":"article","venue":"Hematological Oncology","topic":"CNS Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC; University of British Columbia; BC Cancer Agency","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Genome British Columbia; Genome Canada; Leukemia and Lymphoma Society","keywords":"Diffuse large B-cell lymphoma; Population; Lymphoma; Medicine; Internal medicine; Cumulative incidence; Oncology; Incidence (geometry); Rituximab; Pathology; Cohort","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002059138,0.0002282233,0.0008424615,0.0001965409,0.00007220951,0.000006197653,0.0001279137,0.00035866,0.00004252237],"category_scores_gemma":[0.0001242635,0.0001212095,0.0003518901,0.0008181056,0.00005926534,0.00002350447,0.0000990211,0.0001896243,0.00005749219],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001383311,"about_ca_system_score_gemma":0.0001501101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007497272,"about_ca_topic_score_gemma":0.0006159391,"domain_scores_codex":[0.9980484,0.0002734035,0.0005226214,0.0003590585,0.0002605074,0.0005359874],"domain_scores_gemma":[0.9986471,0.0005145017,0.000233825,0.0004115886,0.00003799484,0.000155002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009877824,0.01093517,0.968701,0.0001797111,0.00008752679,0.002592194,0.0002335563,0.00008146352,0.0003243873,0.008059212,0.004093712,0.003724258],"study_design_scores_gemma":[0.009700335,0.001203413,0.9871682,0.0002321681,0.00009009364,0.0002102953,0.0001206216,0.0004996423,0.00024076,0.00009770941,0.0003312986,0.0001054934],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943005,0.0001386229,0.000001758788,0.0007523383,0.0002391335,0.0007671882,0.00003664085,0.0001322839,0.00363151],"genre_scores_gemma":[0.9991886,0.00008022358,0.00004471545,0.0001643909,0.00004816668,0.00009752233,0.00009053724,0.00002065427,0.0002652137],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01846714,"threshold_uncertainty_score":0.494278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02135789719110921,"score_gpt":0.3165275602961005,"score_spread":0.2951696631049913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}