{"id":"W4380150585","doi":"10.1016/j.jval.2023.03.209","title":"CO136 Efficacy and Safety of Roflumilast Cream 0.15% in Adults and Children Aged 6 and Older with Mild to Moderate Atopic Dermatitis in Two Phase 3 Integument Trials","year":2023,"lang":"en","type":"article","venue":"Value in Health","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; Probity Medical Research; Queen's University","funders":"","keywords":"Roflumilast; Atopic dermatitis; Medicine; Dermatology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00182936,0.0007961357,0.001979819,0.0002992761,0.0003183876,0.0008231371,0.0004928142,0.00106191,0.003065124],"category_scores_gemma":[0.001580611,0.0004025488,0.002160536,0.0002625027,0.0005068601,0.0006891201,0.0003297602,0.001793077,0.0005310959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006495728,"about_ca_system_score_gemma":0.000770729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001111867,"about_ca_topic_score_gemma":0.003277992,"domain_scores_codex":[0.9990288,0.0005355537,0.00007983217,0.0001225189,0.00009780076,0.0001355313],"domain_scores_gemma":[0.9992035,0.0002984968,0.0001859175,0.00005304007,0.00008538044,0.0001735896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8751765,0.00884549,0.005365095,0.002071778,0.003020314,0.000145864,0.0002731781,0.0004287415,0.01408905,0.0002065747,0.00159267,0.0887847],"study_design_scores_gemma":[0.7199391,0.23777,0.03264413,0.0001837732,0.002362398,0.0002762889,0.0001437146,0.0004807328,0.00261546,0.0001545703,0.003376707,0.0000531922],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9833921,0.01156546,0.0003049777,0.0004458277,0.0001958863,0.001176763,0.0007585513,0.00005103678,0.002109454],"genre_scores_gemma":[0.9916558,0.003937757,0.0006453192,0.000434303,0.0001532576,0.0009198421,0.0006772469,0.00001466068,0.001561852],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003065124,"threshold_uncertainty_score":0.01025391,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03040579141262,"score_gpt":0.3500039181887003,"score_spread":0.3195981267760803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}