{"id":"W4380152961","doi":"10.51731/cjht.2023.668","title":"Brexucabtagene Autoleucel (Tecartus)","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Reimbursement; Medicine; Refractory (planetary science); Chimeric antigen receptor; Drug; Intensive care medicine; Family medicine; Pharmacology; Internal medicine; Political science; Cancer; Immunotherapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001208987,0.0001243913,0.0004456097,0.001667973,0.0002054969,0.00003044317,0.0003367253,0.0001748649,0.0004406691],"category_scores_gemma":[0.0006745132,0.0001056208,0.0001102795,0.001319233,0.0002574811,0.00006614892,0.0000312115,0.000725033,0.0001057753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006129533,"about_ca_system_score_gemma":0.005236642,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003104332,"about_ca_topic_score_gemma":0.002096539,"domain_scores_codex":[0.9981899,0.00005182342,0.0005178167,0.0001459839,0.0003215438,0.0007729142],"domain_scores_gemma":[0.9989071,0.00006949723,0.0001951412,0.0003790698,0.0002034663,0.000245654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003027891,0.00001202078,0.004217265,0.0001352812,0.00006397068,0.001204386,0.0002503324,0.00001010786,0.003674461,0.0003388028,0.04376576,0.9462973],"study_design_scores_gemma":[0.0009136066,0.0009182039,0.02270704,0.0002811842,0.00001325522,0.001238504,0.003194989,0.00005044395,0.003843794,0.001075239,0.9656342,0.0001295019],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7043509,0.04441793,0.0000955645,0.2432318,0.001228547,0.0008506382,0.00004450161,0.001007948,0.004772155],"genre_scores_gemma":[0.9934191,0.00168317,0.0002964643,0.0007359206,0.00004051451,0.000007215902,0.000006284055,0.00003417086,0.003777207],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9461678,"threshold_uncertainty_score":0.9289577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06782205487796064,"score_gpt":0.3562780262120117,"score_spread":0.2884559713340511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}