{"id":"W4380291366","doi":"10.2217/fon-2022-1289","title":"Plain language summary of the updated results from the CROWN study comparing lorlatinib with crizotinib in people with advanced non-small-cell lung cancer","year":2023,"lang":"en","type":"article","venue":"Future Oncology","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"National Comprehensive Cancer Network; Pfizer","keywords":"Crizotinib; Medicine; Lung cancer; Crown (dentistry); Oncology; Internal medicine; Dentistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01034858,0.002021166,0.005583461,0.005911904,0.0005737588,0.004299051,0.003563768,0.002793095,0.07398879],"category_scores_gemma":[0.07108535,0.001124393,0.00758124,0.009543003,0.0005005775,0.003049984,0.001442308,0.004068209,0.01990506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002892765,"about_ca_system_score_gemma":0.005062948,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01639065,"about_ca_topic_score_gemma":0.01819861,"domain_scores_codex":[0.9870893,0.00392765,0.004037716,0.0008039088,0.003540069,0.0006012486],"domain_scores_gemma":[0.9254662,0.03644623,0.0118906,0.00159069,0.02321816,0.001388103],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001706315,0.00002854757,0.0008796037,0.03277908,0.001434622,0.00008058563,0.00005340393,0.000158788,0.0001541899,0.0003217479,0.9291996,0.03320344],"study_design_scores_gemma":[0.00597909,0.0007041257,0.02280336,0.0454359,0.008363785,0.0004588563,0.0002091865,0.0001696799,0.0003689276,0.00138256,0.9138778,0.0002467067],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"dataset","genre_gemma":"other","genre_scores_codex":[0.001791893,0.2222853,0.002540157,0.05722038,0.07748818,0.002394033,0.5996756,0.000841621,0.03576285],"genre_scores_gemma":[0.02750888,0.2675871,0.00889541,0.1921558,0.1003539,0.009518134,0.3475529,0.001557393,0.04487066],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.07398879,"threshold_uncertainty_score":0.2475172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01077462832306809,"score_gpt":0.325115102979017,"score_spread":0.3143404746559489,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}