{"id":"W4380422145","doi":"10.1093/plcell/koad165","title":"Plastid dsRNA transgenes trigger phased small RNA-based gene silencing of nuclear-encoded genes","year":2023,"lang":"en","type":"article","venue":"The Plant Cell","topic":"Photosynthetic Processes and Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Rural and Environment Science and Analytical Services Division","keywords":"Biology; Plastid; RNA silencing; Genetics; Gene silencing; Nuclear gene; Gene; Cell biology; RNA interference; Biogenesis; RNA; Genome; Chloroplast","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002347993,0.0001744744,0.0001849159,0.0000535639,0.0001069559,0.0000131057,0.0003566026,0.0001098661,0.00004433993],"category_scores_gemma":[0.00001788626,0.0001263695,0.0001513091,0.0001425277,0.00005509051,0.000001939123,0.00003807945,0.0000701726,0.00002511509],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005384169,"about_ca_system_score_gemma":0.0001029096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003979253,"about_ca_topic_score_gemma":0.00001817435,"domain_scores_codex":[0.9990219,0.00003994031,0.0002231112,0.0002693065,0.0001443148,0.0003014099],"domain_scores_gemma":[0.999411,0.00005202998,0.0001063696,0.0003189266,0.00004193503,0.00006968772],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002098441,0.00006511017,0.000002348947,0.00006877437,0.00002982741,0.000006640297,0.0001070499,0.0006231122,0.9981402,0.00001048952,0.0002234592,0.0005131291],"study_design_scores_gemma":[0.000742373,0.0001798797,0.000010728,0.00002322875,0.00005513712,0.0000100396,0.0001295427,0.001626149,0.9916076,0.00004510112,0.005401451,0.0001687513],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963847,0.0003968126,0.001793986,0.0001113674,0.0001805831,0.0001815758,0.0002704781,0.00004123924,0.0006392835],"genre_scores_gemma":[0.9984474,0.000528438,0.0002523636,0.0001453013,0.00009776875,0.00001619506,0.0001548308,0.0000342412,0.0003234154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006532596,"threshold_uncertainty_score":0.5153198,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02087395796363519,"score_gpt":0.2084927295331918,"score_spread":0.1876187715695566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}