{"id":"W4380422145","doi":"10.1093/plcell/koad165","title":"Plastid dsRNA transgenes trigger phased small RNA-based gene silencing of nuclear-encoded genes","year":2023,"lang":"en","type":"article","venue":"The Plant Cell","topic":"Photosynthetic Processes and Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Rural and Environment Science and Analytical Services Division","keywords":"Biology; Plastid; RNA silencing; Genetics; Gene silencing; Nuclear gene; Gene; Cell biology; RNA interference; Biogenesis; RNA; Genome; Chloroplast","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000153309,0.0003359525,0.0001971168,0.0001866754,0.0001126151,0.0002696511,0.0002914137,0.0003143148,0.001252372],"category_scores_gemma":[0.0001479046,0.0001873951,0.0002754429,0.0001400067,0.0002740152,0.0001921502,0.0003084266,0.0006821248,0.0006320504],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003177874,"about_ca_system_score_gemma":0.0001821292,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001902667,"about_ca_topic_score_gemma":0.0004290205,"domain_scores_codex":[0.9998119,0.00001886731,0.0000246356,0.00006820464,0.00004937283,0.0000270278],"domain_scores_gemma":[0.9998249,0.00003701695,0.00005888192,0.00003034012,0.00002156046,0.00002728686],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000008153682,0.000004652652,0.00001958507,0.000007602967,8.048385e-7,0.00001289294,0.000006365992,0.00001365237,0.9995387,0.00006617132,0.000006939621,0.0003145192],"study_design_scores_gemma":[0.000008493106,0.0000734632,0.0007109228,0.000002290436,0.000005496525,0.00008386825,0.000009799857,0.0005157621,0.9970047,0.00004877857,0.001534366,0.000002138626],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9543841,0.0009589717,0.03680059,0.0001630638,0.0001106446,0.000160889,0.0008961051,0.0007636684,0.005761886],"genre_scores_gemma":[0.9768814,0.0005695134,0.01269222,0.00008046142,0.00001403813,0.00009776809,0.001174932,0.000178632,0.008310902],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001252372,"threshold_uncertainty_score":0.00418961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02087395796363519,"score_gpt":0.2084927295331918,"score_spread":0.1876187715695566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}