{"id":"W4380447835","doi":"10.1093/ndt/gfad063c_2999","title":"#2999 APABETALONE REDUCES CARDIAC EVENTS IN CKD PATIENTS BY DOWNREGULATING FIBROTIC AND INFLAMMATORY PROCESSES","year":2023,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Resverlogix (Canada)","funders":"","keywords":"Medicine; Mace; Fibrosis; Kidney disease; Inflammation; Internal medicine; Gene expression; Extracellular matrix; Endocrinology; Kidney; Diabetes mellitus; Nephrology; Myocardial infarction; Gene; Cell biology; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002330363,0.0002979781,0.0006724891,0.0001609615,0.0001669464,0.0003667998,0.0001931702,0.0004258332,0.01310441],"category_scores_gemma":[0.0002267649,0.0001055341,0.0004342344,0.0001470324,0.0001352432,0.0002443076,0.0002207964,0.0008820115,0.001817638],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001255257,"about_ca_system_score_gemma":0.0003724979,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007390174,"about_ca_topic_score_gemma":0.001852347,"domain_scores_codex":[0.9998957,0.00002946533,0.0000133116,0.00001429647,0.00003176239,0.00001542347],"domain_scores_gemma":[0.9998424,0.00002887471,0.00003874164,0.000009790994,0.00003731145,0.00004282114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1090841,0.00772656,0.02313898,0.005382103,0.001759939,0.0006552199,0.000120967,0.0005128221,0.3719393,0.0007929265,0.02626073,0.4526264],"study_design_scores_gemma":[0.04525843,0.1758814,0.487214,0.00158875,0.003250285,0.002336694,0.0005393561,0.004090916,0.09949983,0.001947586,0.1782337,0.0001590534],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9040841,0.06441196,0.001285755,0.004191406,0.001264559,0.0006494526,0.007450862,0.0002853928,0.01637653],"genre_scores_gemma":[0.9350377,0.02246586,0.003504382,0.002967608,0.000498343,0.0005306556,0.007160654,0.00004094553,0.02779391],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01310441,"threshold_uncertainty_score":0.04383862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006535514642166783,"score_gpt":0.2268702130154318,"score_spread":0.220334698373265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}