{"id":"W4380536431","doi":"10.3390/cells12121618","title":"Alzheimer’s Disease and Its Possible Evolutionary Origin: Hypothesis","year":2023,"lang":"en","type":"review","venue":"Cells","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Disease; Evolutionary biology; Neuroscience; Biology; Cognitive science; Psychology; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001046657,0.0004814655,0.001231448,0.0003176776,0.0001446777,0.00003828256,0.0001531682,0.0001928652,0.0003874024],"category_scores_gemma":[0.00007063755,0.0003580954,0.0005123339,0.0004386363,0.00009694267,0.00007935791,0.0001482895,0.0002845076,0.006640957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001263022,"about_ca_system_score_gemma":0.001484322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009357012,"about_ca_topic_score_gemma":4.422069e-7,"domain_scores_codex":[0.9977799,0.0001206778,0.0003771386,0.0006539588,0.0005102981,0.000558049],"domain_scores_gemma":[0.9976599,0.0003161795,0.0001245201,0.0004724535,0.00008686231,0.001340043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002678605,0.001233686,0.0001516107,0.05789533,0.06478043,0.008348754,0.00002257052,3.318317e-7,8.283656e-7,0.0002435264,0.05948391,0.8075712],"study_design_scores_gemma":[0.0008189906,0.0001542431,0.0003603122,0.01399535,0.03458112,0.00006945576,0.000006980856,0.00002261572,0.000006774184,0.0002833128,0.949156,0.0005447883],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002621023,0.9959805,1.598538e-7,0.00006964135,0.0001555567,0.00181919,0.0007229116,0.0001529726,0.001072875],"genre_scores_gemma":[0.00005165579,0.9958755,0.00006037864,0.00003467971,0.0003439044,0.0003385411,0.0004549236,0.0001360836,0.002704291],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8896722,"threshold_uncertainty_score":0.9998871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1714068451294074,"score_gpt":0.3865007494658422,"score_spread":0.2150939043364348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}