{"id":"W4380536431","doi":"10.3390/cells12121618","title":"Alzheimer’s Disease and Its Possible Evolutionary Origin: Hypothesis","year":2023,"lang":"en","type":"review","venue":"Cells","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Disease; Evolutionary biology; Neuroscience; Biology; Cognitive science; Psychology; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002169294,0.0006123584,0.0006478445,0.001591339,0.001438938,0.002258101,0.002003694,0.002969382,0.00644572],"category_scores_gemma":[0.003437,0.0002370121,0.0004297874,0.001086751,0.007003434,0.007078697,0.002179733,0.00165117,0.00128874],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008930503,"about_ca_system_score_gemma":0.0008974356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008280571,"about_ca_topic_score_gemma":0.0007387287,"domain_scores_codex":[0.999568,0.0001023006,0.00002112968,0.0001652149,0.00006263242,0.00008066765],"domain_scores_gemma":[0.998753,0.0004800242,0.0001960056,0.00009149429,0.000226372,0.0002532605],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.000872321,0.0004387276,0.07912447,0.001715537,0.0002281579,0.009930234,0.007687076,0.001232583,0.002580229,0.7352041,0.01559454,0.1453921],"study_design_scores_gemma":[0.0001261556,0.0006302859,0.05095011,0.001111154,0.0001537505,0.01670259,0.01125735,0.003826485,0.0006242396,0.8119789,0.1025323,0.0001066742],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.362153,0.1776088,0.02658458,0.2510428,0.005269882,0.0002648871,0.0009601242,0.0001968808,0.175919],"genre_scores_gemma":[0.8788682,0.07261059,0.007984755,0.01424572,0.00675384,0.0002132764,0.0006977497,0.00002895542,0.01859681],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.00644572,"threshold_uncertainty_score":0.02156305,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1714068451294074,"score_gpt":0.3865007494658422,"score_spread":0.2150939043364348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}