{"id":"W4380590260","doi":"10.17116/jnevro2023123051108","title":"Efficacy and safety of the drug Cellex for the treatment of patients with cognitive impairment with chronic cerebral ischemia — results of a multicenter randomized double-blind placebo-controlled clinical trial","year":2023,"lang":"en","type":"article","venue":"S S Korsakov Journal of Neurology and Psychiatry","topic":"Neurological Disorders and Treatments","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Montreal Cognitive Assessment; Placebo; Clinical endpoint; Clinical trial; Randomized controlled trial; Internal medicine; Surrogate endpoint; Cognitive impairment; Anesthesia; Pathology; Disease","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006451663,0.0002337268,0.001018392,0.00008062313,0.0001577876,0.000009380516,0.0001819912,0.00009803742,0.00000663154],"category_scores_gemma":[0.000237259,0.00009198007,0.0003660105,0.0001736121,0.000928409,0.0000505778,0.00004147515,0.0002446201,2.556006e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000005363074,"about_ca_system_score_gemma":0.0001317187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007128323,"about_ca_topic_score_gemma":0.00002422328,"domain_scores_codex":[0.9973052,0.000760037,0.001114566,0.0003232234,0.0002609584,0.0002360222],"domain_scores_gemma":[0.9926404,0.005469124,0.001505471,0.0001950035,0.0001125639,0.00007738009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9755374,0.002722563,0.02019339,0.00002613179,0.0005236547,0.0000048232,0.0002966944,0.00005637005,0.00002492589,0.00003367111,0.00005574501,0.0005246839],"study_design_scores_gemma":[0.9422924,0.02790376,0.0277959,0.00004539021,0.001038999,0.000008093272,0.00003019786,0.0002054396,0.0004315784,0.0001254295,0.00004736139,0.00007546588],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917507,0.0002719598,0.00001267842,0.002371741,0.0005775458,0.00488413,0.00008704751,0.000004949119,0.00003924056],"genre_scores_gemma":[0.9988099,0.0007225827,0.00003317758,0.0002295268,0.00007979554,0.00007129562,0.000002918277,0.00001427893,0.00003656313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03324496,"threshold_uncertainty_score":0.3750838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02885421676761085,"score_gpt":0.3122895736462431,"score_spread":0.2834353568786322,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}