{"id":"W4380626254","doi":"10.1093/ndt/gfad063b_2989","title":"#2989 SELECTIVE RENAL DISPOSITION OF THE CALCINEURIN INHIBITORS VOCLSOPORIN, CYCLOSPORINE, AND TACROLIMUS","year":2023,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Aurinia (Canada)","funders":"","keywords":"Medicine; Pharmacology; Tacrolimus; Pharmacokinetics; Calcineurin; Kidney; Pharmacodynamics; Transplantation; Dialysis; Urology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002538706,0.0002925363,0.000349694,0.0003377366,0.0001628449,0.0003337446,0.0002016332,0.0003294767,0.003090988],"category_scores_gemma":[0.0001440744,0.0001331176,0.0002474647,0.0002107811,0.0002389136,0.000267963,0.0001328818,0.0004635064,0.0006213448],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002886257,"about_ca_system_score_gemma":0.0004076963,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000878309,"about_ca_topic_score_gemma":0.001077208,"domain_scores_codex":[0.9997761,0.00002191968,0.00001456919,0.00004019558,0.0001015144,0.00004574846],"domain_scores_gemma":[0.9998311,0.00002126746,0.00004399161,0.00002008733,0.00003602788,0.0000475034],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004767088,0.00003430418,0.0005367617,0.00006669098,0.00001244602,0.000094551,0.000008893658,0.00006463918,0.9924949,0.0002474586,0.0002904726,0.005672125],"study_design_scores_gemma":[0.00004373546,0.001348337,0.0109768,0.00001812177,0.00004655048,0.001079977,0.00002660407,0.001017019,0.9747751,0.0001215347,0.0105363,0.000009821799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9583102,0.01581096,0.009827686,0.0006040332,0.0002300987,0.0001425796,0.002302951,0.000367238,0.01240423],"genre_scores_gemma":[0.970135,0.005247384,0.006868142,0.0002679827,0.00007775384,0.0001334073,0.001611013,0.00005545074,0.01560386],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003090988,"threshold_uncertainty_score":0.01034033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009661453138700291,"score_gpt":0.2635728733819207,"score_spread":0.2539114202432204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}