{"id":"W4380684059","doi":"10.3390/biomedicines11061705","title":"Age-Related Effects of Exogenous Melatonin on Anxiety-like Behavior in C57/B6J Mice","year":2023,"lang":"en","type":"article","venue":"Biomedicines","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fondazione Umberto Veronesi","keywords":"Open field; Melatonin; Anxiolytic; Psychology; Elevated plus maze; Anxiety; Novelty; Prefrontal cortex; Hippocampus; Developmental psychology; Internal medicine; Neuroscience; Medicine; Psychiatry; Cognition","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002242735,0.0002106521,0.0003465667,0.0007004769,0.00005560247,0.00001010477,0.0002269998,0.000170147,0.00002846523],"category_scores_gemma":[0.0003434659,0.0001802572,0.00008820158,0.002061811,0.0003019419,0.00006660118,0.0000567901,0.0002074693,0.0003619929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004630156,"about_ca_system_score_gemma":0.00005067817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008854968,"about_ca_topic_score_gemma":0.00001228584,"domain_scores_codex":[0.9982052,0.0001061718,0.0003843151,0.0004705996,0.0003830064,0.0004507282],"domain_scores_gemma":[0.998942,0.0004377803,0.0001179547,0.0003372385,0.00002041727,0.0001445916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003290266,0.0001863287,0.005671649,0.0001086119,0.000005514298,0.001440183,0.001222254,0.000005622358,0.9830703,0.001008774,0.001494967,0.005752865],"study_design_scores_gemma":[0.001982084,0.0004895292,0.1640271,0.0003103544,0.00004835415,0.0001238085,0.0001111308,0.00008861624,0.8238587,0.00008755295,0.008599882,0.0002728559],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953412,0.0005584498,0.000001526774,0.0003116942,0.001674487,0.0005742789,0.00001489775,0.0001922576,0.001331166],"genre_scores_gemma":[0.9966077,0.0003937136,0.00001304792,0.0003315155,0.00009237827,0.00007138029,0.00001296288,0.00003649708,0.002440773],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1592116,"threshold_uncertainty_score":0.7350674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01926619835662893,"score_gpt":0.2661422074978744,"score_spread":0.2468760091412454,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}