{"id":"W4380758466","doi":"10.1016/j.burns.2023.06.001","title":"The viable bioengineered allogeneic cellularized construct StrataGraft® synthesizes, deposits, and organizes human extracellular matrix proteins into tissue type-specific structures and secretes soluble factors associated with wound healing","year":2023,"lang":"en","type":"article","venue":"Burns","topic":"Wound Healing and Treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Mallinckrodt Pharmaceuticals; Ikaria","keywords":"Extracellular matrix; Decorin; Laminin; Wound healing; Cell biology; Basement membrane; Secretion; Matrix (chemical analysis); Type I collagen; Medicine; Molecular biology; Immunology; Chemistry; Pathology; Biology; Biochemistry; Proteoglycan","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001527472,0.0004968937,0.0002385365,0.0005539493,0.0001797172,0.0003649832,0.0001984807,0.0002309855,0.002377287],"category_scores_gemma":[0.00008412405,0.0001456506,0.0002300729,0.0002792929,0.0002820857,0.0002869066,0.0001865238,0.0004559394,0.0006684765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002095356,"about_ca_system_score_gemma":0.000398088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005065652,"about_ca_topic_score_gemma":0.0007835433,"domain_scores_codex":[0.9998889,0.000005524609,0.000005593747,0.00002560639,0.00005424622,0.00002012061],"domain_scores_gemma":[0.9998957,0.00001479616,0.00003510004,0.00001412862,0.0000085158,0.00003181769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004294823,0.00001647549,0.0001320671,0.00001311404,0.000002417683,0.00002948086,0.00001418701,0.00003396736,0.9982089,0.0001851513,0.0000297798,0.00129163],"study_design_scores_gemma":[0.00001700325,0.0003378737,0.002681538,0.00000579071,0.00003129539,0.0002554022,0.00002094906,0.0004085577,0.9880311,0.0001031987,0.0081031,0.000004275498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9714939,0.002143698,0.01790193,0.0001069693,0.0001792437,0.0001209168,0.001425406,0.0006880324,0.005939891],"genre_scores_gemma":[0.9754853,0.001171662,0.01126456,0.00005509194,0.00005645168,0.00006736578,0.00223357,0.00007481608,0.009591243],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002377287,"threshold_uncertainty_score":0.007952869,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02597140998604945,"score_gpt":0.2708659064865878,"score_spread":0.2448944965005384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}