{"id":"W4380758466","doi":"10.1016/j.burns.2023.06.001","title":"The viable bioengineered allogeneic cellularized construct StrataGraft® synthesizes, deposits, and organizes human extracellular matrix proteins into tissue type-specific structures and secretes soluble factors associated with wound healing","year":2023,"lang":"en","type":"article","venue":"Burns","topic":"Wound Healing and Treatments","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Mallinckrodt Pharmaceuticals; Ikaria","keywords":"Extracellular matrix; Decorin; Laminin; Wound healing; Cell biology; Basement membrane; Secretion; Matrix (chemical analysis); Type I collagen; Medicine; Molecular biology; Immunology; Chemistry; Pathology; Biology; Biochemistry; Proteoglycan","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002344085,0.0003136585,0.0004323095,0.0001170103,0.0008273263,0.0002131475,0.00009275717,0.0001830804,0.0000315556],"category_scores_gemma":[0.00008696836,0.0002001844,0.00003296014,0.0003872537,0.0002454272,0.00006036499,0.00004756534,0.0002408407,0.000004631599],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008523276,"about_ca_system_score_gemma":0.000105208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003771695,"about_ca_topic_score_gemma":0.0002844358,"domain_scores_codex":[0.9984633,0.00007637189,0.0003058829,0.0003985212,0.000288766,0.00046718],"domain_scores_gemma":[0.9990185,0.0002460906,0.0001223165,0.0002983483,0.0001051638,0.0002095166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000231407,0.0001052945,0.1149819,0.0003420108,0.0011898,0.0003092887,0.001793218,0.00004048039,0.8768003,0.003247403,0.0002014191,0.0007575306],"study_design_scores_gemma":[0.01674897,0.004518723,0.2013274,0.001727958,0.002378848,0.0005020185,0.009217657,0.0009858147,0.7407508,0.007992639,0.01143313,0.002416059],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867756,0.01165817,0.00008864795,0.0001997601,0.0001083693,0.0008804208,0.00002111223,0.0002486317,0.000019241],"genre_scores_gemma":[0.9971165,0.0004573927,0.0008834603,0.000006506609,0.00006308685,0.00001999353,0.0002687707,0.00006607693,0.001118217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1360495,"threshold_uncertainty_score":0.8163283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02597140998604945,"score_gpt":0.2708659064865878,"score_spread":0.2448944965005384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}