{"id":"W4380768000","doi":"10.1038/s41467-023-39281-z","title":"CNK2 promotes cancer cell motility by mediating ARF6 activation downstream of AXL signalling","year":2023,"lang":"en","type":"article","venue":"Nature Communications","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"CIHR Skin Research Training Centre; Fonds de Recherche du Québec - Santé; Université de Montréal; Government of Canada; Canadian Institutes of Health Research; Cancer Research Society; Genome Canada","keywords":"Downstream (manufacturing); Motility; Signalling; Cell biology; Cancer; Chemistry; Cancer research; Biology; Business; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001128321,0.0003453498,0.0001767408,0.0001717852,0.000229988,0.000272349,0.0001728286,0.0002359985,0.00131525],"category_scores_gemma":[0.00007077021,0.00009450234,0.0001872674,0.00012069,0.0001730719,0.0001608032,0.0003000163,0.000408471,0.0003106443],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004875984,"about_ca_system_score_gemma":0.0002797892,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009136042,"about_ca_topic_score_gemma":0.002148696,"domain_scores_codex":[0.9998869,0.00001610616,0.000006654963,0.0000183171,0.00003572987,0.00003627298],"domain_scores_gemma":[0.9999491,0.000004132394,0.00001254975,0.000004436897,0.000005214011,0.00002455732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001571967,0.00001656325,0.0002251977,0.00004255045,0.000003694262,0.00006178739,0.000006342137,0.00007333139,0.9985147,0.0001422065,0.00007833276,0.0006780409],"study_design_scores_gemma":[0.0000407727,0.0001868788,0.01030578,0.000005892929,0.000008878266,0.0004013325,0.00002636772,0.002078627,0.982485,0.00008183915,0.004371393,0.00000727156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938267,0.001211614,0.001646631,0.0002123672,0.00003480965,0.0000191338,0.0003329795,0.000106507,0.002609199],"genre_scores_gemma":[0.9964511,0.0003677239,0.000803687,0.00003289179,0.00000546609,0.00001776436,0.0003019269,0.000007377374,0.002012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00131525,"threshold_uncertainty_score":0.004399896,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02205821843083862,"score_gpt":0.2973992473625282,"score_spread":0.2753410289316896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}