{"id":"W4380785549","doi":"10.1161/circ.146.suppl_1.15061","title":"Abstract 15061: Role of Exosomal Microrna-21a-5p in the Modulation of Ischemia-Induced Angiogenesis in Hypercholesterolemic Conditions","year":2022,"lang":"en","type":"article","venue":"Circulation","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Angiogenesis; Microvesicles; Neovascularization; microRNA; Ischemia; Medicine; Matrigel; Immunology; Cancer research; Cell biology; Biology; Internal medicine; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002189948,0.000352022,0.0004692334,0.0003143786,0.0002037428,0.0003614527,0.0001514652,0.0003677029,0.001593787],"category_scores_gemma":[0.0001955285,0.0001219532,0.0003844273,0.0001692516,0.0002156517,0.0002105533,0.000210788,0.000333438,0.0007011717],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002293254,"about_ca_system_score_gemma":0.0002136886,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002540181,"about_ca_topic_score_gemma":0.0002365369,"domain_scores_codex":[0.999809,0.00002256653,0.00002631111,0.00005388576,0.00006055201,0.00002767275],"domain_scores_gemma":[0.9999089,0.00001555402,0.0000265992,0.00000676275,0.00001767865,0.00002447264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003327795,0.00002460374,0.0003608576,0.0001431409,0.0000134609,0.00009852623,0.00001259866,0.00004100441,0.9961029,0.0001067783,0.0001125333,0.002650822],"study_design_scores_gemma":[0.00005346508,0.0005914744,0.0207716,0.0000366805,0.00009306503,0.0008689572,0.00003550371,0.001422102,0.968654,0.0001899156,0.007269471,0.0000136979],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9750326,0.01323228,0.005515604,0.0003423415,0.0002767368,0.0000907081,0.001648944,0.0002067087,0.003653973],"genre_scores_gemma":[0.9837021,0.003715004,0.005461093,0.0003209476,0.00007269914,0.00009206858,0.002082621,0.00006422049,0.004489196],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001593787,"threshold_uncertainty_score":0.005331814,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01311196881387564,"score_gpt":0.2491591570200257,"score_spread":0.2360471882061501,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}