{"id":"W4380836473","doi":"10.1161/circ.146.suppl_1.15385","title":"Abstract 15385: Integrin Alpha 11 is a Critical Regulator of Cardiac Remodelling, Fibrosis and Infarct Formation Following Myocardial Infarction","year":2022,"lang":"en","type":"article","venue":"Circulation","topic":"Cardiac Fibrosis and Remodeling","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto; St. Michael's Hospital","funders":"","keywords":"Cardiac fibrosis; Medicine; Cardiac function curve; Myocardial infarction; Internal medicine; Fibrosis; Cardiology; Heart failure; Myofibroblast; Extracellular matrix; Fibroblast; Endocrinology; Cell biology; Biology; Cell culture","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001844935,0.000389562,0.0004240925,0.0002393484,0.0002851836,0.000575016,0.0002339143,0.0004700392,0.008273453],"category_scores_gemma":[0.0001483883,0.0002332077,0.000227598,0.0002398935,0.0002139477,0.000220255,0.0002463,0.0008799616,0.002673648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002909437,"about_ca_system_score_gemma":0.0002022711,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004314982,"about_ca_topic_score_gemma":0.000449997,"domain_scores_codex":[0.9997814,0.00002939186,0.00002109768,0.000046978,0.0000726363,0.00004859356],"domain_scores_gemma":[0.9998879,0.000008250127,0.00003680525,0.000005230884,0.00002182942,0.00003995797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002751538,0.0002503135,0.003433367,0.0003973427,0.0000591468,0.0006737532,0.00006854178,0.00007950219,0.9667048,0.0004401334,0.005885588,0.01925601],"study_design_scores_gemma":[0.0008033093,0.004116705,0.4260495,0.0002913319,0.0006144923,0.007722422,0.0006523146,0.002816421,0.449889,0.0008616673,0.1061317,0.00005104555],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9469551,0.0260567,0.003007719,0.002455705,0.001194218,0.0001083075,0.002017332,0.0002957394,0.01790912],"genre_scores_gemma":[0.9525353,0.00685618,0.001191402,0.0008673829,0.0004361159,0.0001488362,0.002670261,0.00005169867,0.03524284],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008273453,"threshold_uncertainty_score":0.02767748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01970876347807165,"score_gpt":0.2727315319869615,"score_spread":0.2530227685088898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}