{"id":"W4380869848","doi":"10.1093/molehr/gaad023","title":"Safety of multiple administrations of spermicidal LL-37 antimicrobial peptide into the mouse female reproductive tract","year":2023,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"Canadian Institutes of Health Research","keywords":"Vagina; Uterus; Cervix; Biology; Fecundity; Sperm; Estrous cycle; Spermicide; Andrology; Intravaginal administration; Genitourinary system; Physiology; Gynecology; Population; Endocrinology; Medicine; Family planning; Anatomy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006139205,0.0002077005,0.0003584237,0.0001408247,0.0004183271,0.00001474597,0.0002452506,0.0001510075,0.00008872934],"category_scores_gemma":[0.0002986516,0.0001788976,0.0002331227,0.0003616223,0.0007346837,0.0001210838,0.0001167501,0.0002923301,0.00006597219],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003418329,"about_ca_system_score_gemma":0.0000698147,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006388885,"about_ca_topic_score_gemma":0.00009188838,"domain_scores_codex":[0.9981754,0.0002238585,0.0005758604,0.0006786507,0.00007237928,0.000273878],"domain_scores_gemma":[0.9983484,0.00005405959,0.0003823378,0.001010138,0.000191,0.00001408821],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001672808,0.0002481843,0.000970651,0.00005382875,0.0001586291,0.000004986662,0.002662866,0.0006436265,0.9914855,0.0008391919,0.001992727,0.0007725078],"study_design_scores_gemma":[0.0004793463,0.000180342,0.007505754,0.00002931819,0.00007324827,0.00005760568,0.001580934,0.000003231568,0.9870034,0.0001481004,0.002763186,0.0001754622],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973608,0.0001948677,0.0001713533,0.0008202904,0.000395583,0.0004814389,0.00006037429,0.0001063121,0.0004089973],"genre_scores_gemma":[0.9940974,0.00006257965,0.0001710482,0.00002825541,0.0001296054,0.00001386472,0.0004033884,0.00003306153,0.005060849],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006535103,"threshold_uncertainty_score":0.7295232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0181883850577996,"score_gpt":0.2618095483937626,"score_spread":0.243621163335963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}