{"id":"W4380869848","doi":"10.1093/molehr/gaad023","title":"Safety of multiple administrations of spermicidal LL-37 antimicrobial peptide into the mouse female reproductive tract","year":2023,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"Canadian Institutes of Health Research","keywords":"Vagina; Uterus; Cervix; Biology; Fecundity; Sperm; Estrous cycle; Spermicide; Andrology; Intravaginal administration; Genitourinary system; Physiology; Gynecology; Population; Endocrinology; Medicine; Family planning; Anatomy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005000646,0.0005438966,0.0005400167,0.0005537727,0.0002038843,0.0003456617,0.0004220979,0.0007432399,0.001049376],"category_scores_gemma":[0.0003542673,0.0002086136,0.0004328786,0.0001931664,0.0004838749,0.0004012618,0.0001789894,0.001136263,0.0003124925],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002361135,"about_ca_system_score_gemma":0.0002976192,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005263855,"about_ca_topic_score_gemma":0.0006286591,"domain_scores_codex":[0.9995052,0.0000916795,0.00003616565,0.0001448151,0.0001248834,0.0000971909],"domain_scores_gemma":[0.999619,0.00005197431,0.0001239342,0.00007736118,0.00004910393,0.00007858843],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007911061,0.000295268,0.0005071616,0.00006435699,0.00001251361,0.00008567797,0.00004702831,0.00007936009,0.9944111,0.00007964601,0.00006988439,0.003556781],"study_design_scores_gemma":[0.00006864786,0.01098214,0.003876994,0.00002505883,0.00004383214,0.0003091366,0.00006336047,0.0007501678,0.9818595,0.00006262111,0.001946146,0.000012499],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9905714,0.003354637,0.003936694,0.0001500805,0.00008708285,0.0001588854,0.0005004929,0.0001880532,0.001052773],"genre_scores_gemma":[0.9875547,0.002523208,0.004789839,0.0001540907,0.00004983346,0.0003994759,0.0006217849,0.00004475298,0.0038624],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001049376,"threshold_uncertainty_score":0.003510475,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0181883850577996,"score_gpt":0.2618095483937626,"score_spread":0.243621163335963,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}