{"id":"W4380870296","doi":"10.1159/000531468","title":"Sequence Similarity among Structural Repeats in the Piezo Family of Mechanosensitive Ion Channels","year":2023,"lang":"en","type":"article","venue":"Microbial Physiology","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Wilfrid Laurier University","funders":"National Institute of General Medical Sciences; University of California, San Diego; National Institutes of Health","keywords":"Genetics; Structural similarity; Biology; Direct repeat; Similarity (geometry); Sequence (biology); Computational biology; Repeated sequence; Sequence alignment; Peptide sequence; Genome; Gene; Biochemistry; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000269958,0.0001413293,0.0003380247,0.0009132422,0.0002304608,0.0002359342,0.0001567785,0.0002779257,0.001193266],"category_scores_gemma":[0.000980345,0.00008342561,0.0003571403,0.0008883601,0.0001640171,0.0002792642,0.0002285378,0.000220095,0.0005204136],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001788456,"about_ca_system_score_gemma":0.0002688048,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008826442,"about_ca_topic_score_gemma":0.001341488,"domain_scores_codex":[0.9997821,0.00003271458,0.00002754647,0.0000763691,0.000055364,0.00002580159],"domain_scores_gemma":[0.9994658,0.0001832894,0.0001622596,0.00003821765,0.00007473454,0.00007581015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001465047,0.0002061779,0.1828427,0.0004866647,0.0002226484,0.001075041,0.0006561462,0.003893691,0.7648821,0.001035582,0.0008204264,0.0424138],"study_design_scores_gemma":[0.00007183009,0.0007294292,0.8621413,0.00009161669,0.0002685896,0.003930595,0.0004117884,0.04054051,0.08432416,0.002194822,0.005195481,0.00009982945],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926232,0.0004478156,0.004914236,0.00002794268,0.000006576094,0.00002446444,0.001220041,0.0000888413,0.0006469252],"genre_scores_gemma":[0.9926062,0.0001175639,0.00453763,0.00002289707,0.000006081132,0.000018406,0.002474271,0.00001315094,0.0002038868],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001193266,"threshold_uncertainty_score":0.003991842,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0407184670359137,"score_gpt":0.2909483499033252,"score_spread":0.2502298828674115,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}