{"id":"W4380993043","doi":"10.1016/j.xkme.2023.100688","title":"Novel Therapeutics for Management of Lupus Nephritis: What Is Next?","year":2023,"lang":"en","type":"article","venue":"Kidney Medicine","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Lupus nephritis; Medicine; Systemic lupus erythematosus; Intensive care medicine; Nephrology; Nephritis; Clinical trial; Immunology; Internal medicine; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001037493,0.0002197709,0.0006391443,0.0003701853,0.00006408874,0.00002109795,0.0002506264,0.0001425586,0.0003375445],"category_scores_gemma":[0.0001706602,0.0001641303,0.0001343828,0.0008902617,0.0002227645,0.0001657706,0.0001054633,0.0001724845,0.0001082502],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009198328,"about_ca_system_score_gemma":0.0001481497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000300497,"about_ca_topic_score_gemma":0.000001104619,"domain_scores_codex":[0.9973952,0.00002724558,0.000597457,0.0003866837,0.001061142,0.0005322938],"domain_scores_gemma":[0.9981683,0.0002346859,0.0001303557,0.0007064393,0.0003309578,0.0004292116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00107296,0.0004053693,0.00827665,0.02129093,0.002252675,0.0002462658,0.01123246,0.000001546085,0.107452,0.003602709,0.7353379,0.1088286],"study_design_scores_gemma":[0.03603781,0.002068283,0.001571531,0.03283327,0.001264147,0.004883894,0.05541678,0.003790388,0.008614725,0.001461834,0.8515289,0.0005284468],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.3292668,0.05977292,0.01889453,0.506758,0.01989236,0.02276953,0.0004177227,0.001983514,0.04024466],"genre_scores_gemma":[0.5145541,0.1564458,0.01842219,0.06939609,0.005675233,0.002468018,0.00164893,0.0008372802,0.2305523],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.4373619,"threshold_uncertainty_score":0.669304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09055795166749943,"score_gpt":0.3675270263475855,"score_spread":0.2769690746800861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}