{"id":"W4381113094","doi":"10.1136/gutjnl-2023-bsg.123","title":"P51 Benefit-risk of upadacitinib in patients with moderately to severe ulcerative colitis (UC)","year":2023,"lang":"en","type":"article","venue":"Poster presentations","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Medicine; Clinical endpoint; Gastroenterology; Internal medicine; Placebo; Confidence interval; Phases of clinical research; Randomized controlled trial; Surgery; Clinical trial; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000866016,0.0002562976,0.0007096126,0.0001603573,0.0001342604,0.0004690221,0.0001568114,0.0003744761,0.002751301],"category_scores_gemma":[0.001570814,0.0001027291,0.0009351698,0.0002253237,0.0001778385,0.0002620439,0.0002572366,0.0006439943,0.0002113958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002668468,"about_ca_system_score_gemma":0.0002830043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003106182,"about_ca_topic_score_gemma":0.0008690684,"domain_scores_codex":[0.9996438,0.0001840338,0.00002672231,0.00004629767,0.00004927948,0.0000498695],"domain_scores_gemma":[0.9994791,0.0002500358,0.0001365409,0.00002726629,0.00001864641,0.00008848696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.407977,0.001088122,0.09626614,0.002162239,0.003812879,0.001014838,0.0001289641,0.003154891,0.01645835,0.0007508265,0.008005876,0.4591798],"study_design_scores_gemma":[0.06755222,0.1142931,0.7741905,0.00056045,0.00881715,0.003292425,0.0001983309,0.006008868,0.006663641,0.002776572,0.01553063,0.0001162517],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9696118,0.02326898,0.0007275423,0.001530527,0.0001594814,0.0001919716,0.0009176037,0.00005032706,0.00354182],"genre_scores_gemma":[0.9975365,0.001380947,0.0001942656,0.0002387205,0.00008335419,0.00003408484,0.0002614479,0.000003007247,0.0002676372],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002751301,"threshold_uncertainty_score":0.00920397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009302863945968014,"score_gpt":0.2519886369935889,"score_spread":0.2426857730476209,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}