{"id":"W4381194708","doi":"10.1016/j.jcis.2023.06.122","title":"Novel bioactive cationic cubosomes enhance the cytotoxic effect of paclitaxel against a paclitaxel resistant prostate cancer cell-line","year":2023,"lang":"en","type":"article","venue":"Journal of Colloid and Interface Science","topic":"Lipid Membrane Structure and Behavior","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"RMIT University; Council of Scientific and Industrial Research, India; Ontario Ministry of Natural Resources and Forestry","keywords":"Chemistry; Cationic polymerization; Cytotoxicity; Paclitaxel; In vitro; Organic chemistry; Biochemistry; Cancer; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008612915,0.0001320797,0.0002068288,0.00007317393,0.0001561265,0.00004684654,0.0003376028,0.00004914598,0.000004857004],"category_scores_gemma":[0.0001684155,0.00007533687,0.00008460007,0.0004119429,0.0004899866,0.0000345864,0.00010933,0.0001246629,8.163013e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003974776,"about_ca_system_score_gemma":0.0003338016,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003044414,"about_ca_topic_score_gemma":0.00004554644,"domain_scores_codex":[0.9988945,0.00004741031,0.000321007,0.0002153773,0.0002986149,0.0002231221],"domain_scores_gemma":[0.9990078,0.00004176744,0.0003704602,0.0001976866,0.0002995719,0.00008271544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002135046,0.00002335324,0.0002266561,0.00003400509,0.00001861636,3.758116e-7,0.0003204242,0.00008942117,0.9982833,0.00000390165,0.0001917782,0.0005946658],"study_design_scores_gemma":[0.0005068328,0.001200515,0.001692249,0.00007487142,0.00003242486,0.00001259922,0.00040626,0.0000659433,0.995064,0.000004100795,0.0008483088,0.00009189088],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977509,0.001082686,0.0000578541,0.0003256474,0.000390137,0.000217204,0.00004483954,0.0000031907,0.0001274753],"genre_scores_gemma":[0.9972249,0.001805792,0.00005713298,0.00005327846,0.0001416446,0.00001077947,0.000001565101,0.000008275834,0.0006966486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003219294,"threshold_uncertainty_score":0.3072149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007129114003870448,"score_gpt":0.2978487338516557,"score_spread":0.2907196198477853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}