{"id":"W4381251839","doi":"10.1016/j.celrep.2023.112648","title":"Polysialylation controls immune function of myeloid cells in murine model of pneumococcal pneumonia","year":2023,"lang":"en","type":"article","venue":"Cell Reports","topic":"Pneumonia and Respiratory Infections","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Office of Research Infrastructure Programs, National Institutes of Health; National Institute of General Medical Sciences; National Institutes of Health; National Cancer Institute; Fonds de recherche du Québec – Nature et technologies; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; School of Medicine, University of Maryland","keywords":"Immune system; Myeloid; Biology; Adoptive cell transfer; Immunology; Sialic acid; Pneumonia; Streptococcus pneumoniae; Bone marrow; Cell biology; T cell; Microbiology; Medicine; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002654094,0.0005250756,0.000334218,0.0004934624,0.0002152427,0.0003314119,0.0002499395,0.0004771556,0.001377748],"category_scores_gemma":[0.0001191262,0.000204808,0.0002985704,0.0002029736,0.0004487072,0.0003374044,0.0002615616,0.001628885,0.0004693924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003146392,"about_ca_system_score_gemma":0.0002737551,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003354323,"about_ca_topic_score_gemma":0.0006579377,"domain_scores_codex":[0.9996327,0.0000657637,0.00003279906,0.00006867301,0.00008044278,0.000119638],"domain_scores_gemma":[0.9998362,0.000009885885,0.00005273994,0.00001701112,0.00001266901,0.00007149896],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00110219,0.0003402414,0.0005531732,0.00006701009,0.00000581369,0.000113668,0.00006635211,0.000137275,0.995037,0.0002156686,0.00009290688,0.002268621],"study_design_scores_gemma":[0.0001494703,0.005732896,0.01672678,0.00002804447,0.00005189198,0.0004941653,0.0001839772,0.002708362,0.9692536,0.0002819391,0.00437003,0.00001878433],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.995205,0.001181234,0.00149002,0.0001461762,0.00006251409,0.00007731218,0.0005070561,0.00006590209,0.001264813],"genre_scores_gemma":[0.9929377,0.0009329952,0.001804738,0.00008538345,0.00002228214,0.0001758389,0.0004742844,0.00001911709,0.003547647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001377748,"threshold_uncertainty_score":0.004609048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01469667666782991,"score_gpt":0.246188694698352,"score_spread":0.2314920180305221,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}