{"id":"W4381378525","doi":"10.2337/db23-1598-p","title":"1598-P: MIF-upregulated CD74 in Liver Contributes to the Development of NAFLD","year":2023,"lang":"en","type":"article","venue":"Diabetes","topic":"Macrophage Migration Inhibitory Factor","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Manitoba Beekeepers' Association","funders":"","keywords":"Macrophage migration inhibitory factor; CD74; Downregulation and upregulation; Inflammation; Internal medicine; Endocrinology; Proinflammatory cytokine; Nonalcoholic fatty liver disease; Cytokine; Medicine; Biology; Immunology; Fatty liver; Immune system; T cell; Disease; Biochemistry; Gene; MHC class II","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002909724,0.00009941247,0.0001823443,0.0001463993,0.00008511994,0.000007977857,0.0001816444,0.0001058515,0.0005540785],"category_scores_gemma":[0.0002015444,0.00006482383,0.00003257112,0.000442002,0.00006821706,0.00002866557,0.00009318243,0.00009501502,0.001372827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002803798,"about_ca_system_score_gemma":0.00005916315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001159689,"about_ca_topic_score_gemma":0.0001617992,"domain_scores_codex":[0.9991441,0.0001098313,0.0002980129,0.0001552649,0.00002864817,0.0002641483],"domain_scores_gemma":[0.9993553,0.0003467827,0.00005572198,0.0001722607,0.00005874284,0.00001116148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000452902,0.00004469039,0.02133227,0.00002596217,0.0001038977,0.000001796905,0.00373612,0.00003165437,0.9438442,0.00008698425,0.02447965,0.006267467],"study_design_scores_gemma":[0.0004391931,0.00002899594,0.1023878,0.00004535976,0.000006062944,1.680538e-7,0.0002527789,0.00002135986,0.8494755,0.00002091166,0.04724038,0.00008145881],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980993,0.0007564656,0.00002014529,0.000286476,0.0003652098,0.0002854803,0.00003038741,0.00006220963,0.00009431098],"genre_scores_gemma":[0.9961331,0.000004133892,0.00006673074,0.0001622996,0.00001017962,0.00007071922,0.0000849807,0.000008693814,0.003459187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09436873,"threshold_uncertainty_score":0.9994047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01396128690831825,"score_gpt":0.2281981578348398,"score_spread":0.2142368709265215,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}