{"id":"W4381383527","doi":"10.1093/bjd/ljad162.033","title":"413 Improvement in itch, symptoms and quality of life with upadacitinib through week 16 in adults and adolescents with atopic dermatitis: results from phase 3 studies (Measure Up 1, Measure Up 2 and AD Up)","year":2023,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Medicine; Placebo; Atopic dermatitis; Post-hoc analysis; Internal medicine; Quality of life (healthcare); Dermatology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002173719,0.0003434028,0.001345852,0.0002556221,0.0002302311,0.0005764989,0.0002308584,0.0004027994,0.001390434],"category_scores_gemma":[0.001114609,0.0001912472,0.001686226,0.0003506913,0.000244189,0.0003779269,0.0002725064,0.0009074593,0.0001695029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003783554,"about_ca_system_score_gemma":0.0005171776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006024442,"about_ca_topic_score_gemma":0.001582668,"domain_scores_codex":[0.9992964,0.0003356575,0.00009442325,0.00008529519,0.0001111877,0.0000770389],"domain_scores_gemma":[0.9992436,0.0001715368,0.0002920218,0.00004329265,0.0001115644,0.0001379257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5246024,0.02120987,0.1067997,0.004956469,0.009168276,0.0002789588,0.0005116468,0.001405943,0.0417076,0.0001544363,0.003719427,0.2854854],"study_design_scores_gemma":[0.1265427,0.3780693,0.4659074,0.0005496414,0.00876403,0.0006005892,0.0003353826,0.001536733,0.01175537,0.0001670089,0.005697974,0.00007389684],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903349,0.007580614,0.0002014767,0.0001027801,0.00003244723,0.0004788256,0.0006905147,0.0000173758,0.0005610428],"genre_scores_gemma":[0.9959236,0.001994471,0.0004634284,0.0001943828,0.00003247641,0.0003904729,0.0006974525,0.000004319238,0.0002993296],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002173719,"threshold_uncertainty_score":0.01149589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03351757199696836,"score_gpt":0.3050932978455515,"score_spread":0.2715757258485831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}