{"id":"W4381434619","doi":"10.1158/1078-0432.ccr-22-3815","title":"The Prognostic Effect of Immune Cell Infiltration Depends on Molecular Subtype in Endometrioid Ovarian Carcinomas","year":2023,"lang":"en","type":"article","venue":"Clinical Cancer Research","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Occupational Cancer Research Centre; Vancouver General Hospital; University of British Columbia","funders":"U.S. Army Medical Research and Development Command; National Cancer Institute; AstraZeneca; Novocure; National Health and Medical Research Council; Canadian Institutes of Health Research; National Institutes of Health; Janet D. Cottrelle Foundation; Medical Research Council; PharmaMar; Medical Research and Materiel Command; Eisai; European Commission; BC Cancer Foundation; Seagen; Deutsche Forschungsgemeinschaft; VGH and UBC Hospital Foundation; Marshfield Clinic Research Foundation; Amgen; Mersana Therapeutics; Stryker; Victorian Cancer Agency; Michael Smith Health Research BC; Memorial Sloan-Kettering Cancer Center","keywords":"Immune system; Serous fluid; Biology; Serous carcinoma; Clear cell; Carcinoma; Clear cell carcinoma; Ovarian carcinoma; Pathology; Cancer research; Immunohistochemistry; Ovarian cancer; Immunology; Medicine; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007161819,0.0001699135,0.0002556783,0.0005975748,0.000184048,0.0003477449,0.0002095008,0.0002266556,0.0006960226],"category_scores_gemma":[0.001401999,0.0001252591,0.0002415571,0.0003329844,0.0002658115,0.0002762332,0.0004103817,0.0001901923,0.0001280172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002039875,"about_ca_system_score_gemma":0.0001078427,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005736724,"about_ca_topic_score_gemma":0.001083673,"domain_scores_codex":[0.9997664,0.00007100386,0.00002518432,0.00005131075,0.00004454415,0.00004158014],"domain_scores_gemma":[0.9991735,0.0002625271,0.0002815843,0.00008447876,0.00008708123,0.0001108754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006725276,0.0000112444,0.9913222,0.00001614213,0.00002946823,0.0000924338,0.00004176191,0.00006426254,0.003863392,0.00001214391,0.00002163854,0.003852858],"study_design_scores_gemma":[0.000006693053,0.0001217262,0.9981838,0.000006349947,0.00002801455,0.0004995621,0.0001012763,0.0002482921,0.0006388719,0.00003323417,0.0001297482,0.000002402288],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992085,0.0005081641,0.00008444709,0.000007131012,0.000001340447,0.000003246816,0.0000355671,0.000002327617,0.0001492763],"genre_scores_gemma":[0.9996998,0.00009935967,0.00007973448,0.000003987838,0.000002630808,0.000002956108,0.00006017796,0.000001115445,0.00005034655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007161819,"threshold_uncertainty_score":0.003787577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1007175274008238,"score_gpt":0.4737054319116363,"score_spread":0.3729879045108124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}