{"id":"W4381511311","doi":"10.5267/j.ccl.2023.3.010","title":"Synthesis, characterization and biological study of some new substituted pyrazolo[3,4-d] thiazolo[3,2-a] pyrimidine derivatives","year":2023,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Saurashtra University; Department of Science and Technology, Ministry of Science and Technology, India","keywords":"Chemistry; Thiourea; Potassium carbonate; Antibacterial activity; Pyrimidine; Catalysis; Benzaldehyde; Acetic acid; Aryl; Organic chemistry; Ethyl acetoacetate; Medicinal chemistry; Methanol; Nuclear chemistry; Stereochemistry; Alkyl; Bacteria","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000109148,0.0002166595,0.000227025,0.0002417898,0.000136221,0.0001851786,0.0001636929,0.0002148494,0.0006880655],"category_scores_gemma":[0.0001905479,0.00008327697,0.0001910741,0.0002384928,0.000116743,0.0001968249,0.00009244378,0.0002547345,0.0001876952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001521878,"about_ca_system_score_gemma":0.0001341983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005396928,"about_ca_topic_score_gemma":0.0009952058,"domain_scores_codex":[0.9999313,0.00001040712,0.000007680228,0.00001489369,0.00002431636,0.00001138845],"domain_scores_gemma":[0.9999017,0.00001375253,0.00002799033,0.000007496458,0.0000307489,0.00001830124],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004774285,0.0000327466,0.0001465647,0.000139303,0.000004774105,0.00009020911,0.00002117292,0.0001861039,0.9972413,0.00004842126,0.00003511683,0.002006628],"study_design_scores_gemma":[0.00001599453,0.00149008,0.003871392,0.00001526978,0.00003414599,0.0004976831,0.0000414423,0.0006608621,0.9869754,0.0000389987,0.006345472,0.00001331262],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9794216,0.01335514,0.003751927,0.0001310176,0.00004208673,0.00008960683,0.0009527097,0.00005529448,0.002200661],"genre_scores_gemma":[0.9831086,0.006624404,0.006561417,0.00005668299,0.00002202646,0.0000556755,0.0009976425,0.00001173703,0.002561868],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006880655,"threshold_uncertainty_score":0.002301872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05906212727044342,"score_gpt":0.270427107295426,"score_spread":0.2113649800249826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}