{"id":"W4381598611","doi":"10.1177/03635465231179223","title":"Clinical Efficacy and Safety of the Intra-articular Injection of Autologous Adipose-Derived Mesenchymal Stem Cells for Knee Osteoarthritis: A Phase III, Randomized, Double-Blind, Placebo-Controlled Trial","year":2023,"lang":"en","type":"article","venue":"The American Journal of Sports Medicine","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Osteoarthritis; WOMAC; Visual analogue scale; Placebo; Randomized controlled trial; Clinical trial; Knee pain; Clinical endpoint; Surgery; Physical therapy; Internal medicine; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["sts"],"consensus_categories":[],"category_scores_codex":[0.0146511,0.0002938609,0.003882273,0.000394044,0.000140128,0.00000869693,0.0003169657,0.000107912,0.0000901082],"category_scores_gemma":[0.0015287,0.0001390162,0.0007630365,0.0009370482,0.003031077,0.0000583752,0.0000927592,0.0007251498,0.000001212584],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005176674,"about_ca_system_score_gemma":0.0005199484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005755481,"about_ca_topic_score_gemma":0.000003000202,"domain_scores_codex":[0.9934989,0.0009639049,0.003362442,0.0002960729,0.001426719,0.0004520245],"domain_scores_gemma":[0.9901813,0.004682062,0.00350558,0.0005459747,0.0007186485,0.0003664893],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8932433,0.0003142787,0.0001105159,0.00007877898,0.0009676329,0.0001079753,0.001166297,0.00008476553,0.006483396,0.00002853396,0.0002684352,0.09714612],"study_design_scores_gemma":[0.9690235,0.02104056,0.0004596389,0.001034634,0.002345404,0.0005685249,0.002227902,0.0006244172,0.002374602,0.00005972587,0.0001276561,0.0001134192],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851822,0.001313467,0.0004040092,0.002935535,0.001012148,0.00898383,0.000004716493,0.00002208334,0.0001419827],"genre_scores_gemma":[0.9975521,0.0009927945,0.0001292659,0.0001240993,0.0007486551,0.00009164561,0.000003253938,0.00003767558,0.0003204943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0970327,"threshold_uncertainty_score":0.9996821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03697486083048974,"score_gpt":0.3569559955137627,"score_spread":0.319981134683273,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}