{"id":"W4381598611","doi":"10.1177/03635465231179223","title":"Clinical Efficacy and Safety of the Intra-articular Injection of Autologous Adipose-Derived Mesenchymal Stem Cells for Knee Osteoarthritis: A Phase III, Randomized, Double-Blind, Placebo-Controlled Trial","year":2023,"lang":"en","type":"article","venue":"The American Journal of Sports Medicine","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":119,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Osteoarthritis; WOMAC; Visual analogue scale; Placebo; Randomized controlled trial; Clinical trial; Knee pain; Clinical endpoint; Surgery; Physical therapy; Internal medicine; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004442766,0.00231954,0.005814704,0.0006900327,0.00072351,0.001748053,0.00127167,0.003057837,0.005540046],"category_scores_gemma":[0.003413484,0.001062249,0.003088294,0.0006664053,0.002062397,0.001350046,0.000470422,0.002542201,0.001187303],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007394282,"about_ca_system_score_gemma":0.002052833,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004993234,"about_ca_topic_score_gemma":0.0008834957,"domain_scores_codex":[0.9980692,0.001000136,0.0001868065,0.0003595155,0.0001894288,0.0001948911],"domain_scores_gemma":[0.9978788,0.0006267935,0.0006516357,0.0001848075,0.0002191272,0.0004388631],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9814991,0.007707343,0.0002698835,0.0008859509,0.0006669643,0.00001624291,0.0000333001,0.0001433878,0.002221493,0.00005028942,0.0002317444,0.006274199],"study_design_scores_gemma":[0.9453818,0.05323077,0.0004256798,0.00003378454,0.0003117396,0.000009739685,0.000007509339,0.0001647236,0.000243728,0.00004021272,0.0001425822,0.00000766436],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9613488,0.01204703,0.002423521,0.0009693437,0.001128601,0.01846478,0.001353871,0.0002269311,0.00203704],"genre_scores_gemma":[0.9584066,0.00576849,0.004936183,0.001635843,0.001024522,0.02445842,0.001190614,0.00004896284,0.00253047],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005814704,"threshold_uncertainty_score":0.02349585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03697486083048974,"score_gpt":0.3569559955137627,"score_spread":0.319981134683273,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}